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• W2186320637 abstract "Amomum is a genus of terrestrial, rhizomatous herb, distributed chiefly in Africa and tropical Asia, found in the eastern Himalayas and cultivated in Nepal, northern West Bengal, Sikkim and Assam hills (1). In folk medicine, the seeds are credited with stimulant, stomachic, alexipharmic and astringent properties, and are prescribed for the treatment of indigestion, vomiting, biliousness, abdominal pains and rectal diseases. They promote elimination of bile and are useful in congestion of liver; they are also used in gonorrhea. The pericarp is useful in headache and heals stomatitis. The aromatic oil extracted from the seeds is applied to the eyes to allay inflammation (1). The seeds contained the glycosides petunidin 3,5-diglucoside and leucocynidin-3-O-β-D-glucopyranoside, and a new aurone glycoside, subulin. The presence of chalcone, cardamonin and a flavanone, alpinetin was also reported (1). The seeds on steam distillation yield a dark brown, mobile essential oil [2.5%] having a characteristic odor of cineol (1). Essential oil of A. subulatum has been studied extensively for its composition and its antimicrobial potential (2n6). Nigam and Purohit (7) obtained 2.5% oil from the seeds and fractionated the oil into different cineole-rich fractions. Lawrence (8) separated the components of the oil by preparative gas chromatography and identified them by their IR spectra and retention data and found the major component 1,8-cineole in 74%. Patra et al. (9) studied the oil by packed column GC and reported that it contains sabinene (9.1%), γ-terpinene (16.2%), 1,8-cineole (63.3%) as major components. In a latter study, Gupta et al. (10) have analyzed oils derived from different strains of A. subulatum growing wild in Sikkim and found 1,8-cineole content to vary from 77 to 89%. The oil and volatile concentrate produced by liquid carbon dioxide extraction of A. subulatum have been compared (11). More recently Gurudutt et al. (12) analyzed the oil using GC/MS and identified 25 components of which 16.3% were monoterpene hydrocarbons and 75.3% were of oxygenated monoterpenes with 1,8-cineole (61.3%), being the major component. In the current study, chemical composition of essential oil isolated from fruits of A. subulatum obtained from Himachal Pradesh, India was determined and its potential as antimicrobial and antiinflammatory agent has been studied." @default.
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• W2186320637 date "2013-01-05" @default.
• W2186320637 modified "2023-09-25" @default.
• W2186320637 title "Chemical composition, antimicrobial and topical anti-inflammatory activity of essential oil of Amomum subulatum fruits." @default.
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