FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2186352302> ?p ?o ?g. }

• W2186352302 abstract "Background. The toxic effect of exposure to cadmium and copper is a result of their concentrations and interac− tions in the body. Free radical mechanisms and disorders of zinc metabolism have been implicated in the damage of kidneys caused by Cd and Cu. Physical exercise causes the oxidative stress and also changes the metal distrib− ution and disturbs its metabolism. On the other hand, moderate physical training influences favourably on the antioxidative protection and can reduce the toxic effect caused by cadmium and copper. Objectives. The aim of this study was to investigate the influence of both physical training and intoxication with cadmium, copper, and cadmium and copper simultaneously on the concentrations of metals (Cd, Zn, Cu) in the blood and kidneys; the concentration of indicators of oxidative stress (malonyldialdehyd (MDA), sulfhydryl groups) in the kidneys of rats; and the changes in some antioxidant components such as: superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) and reduced glutathione (GSH). Material and Methods. Fifty−four rats (female, Buffalo strain) were split into 9 groups of 6 rats each. One group represented the control and eight groups were intoxicated with cadmium (50 ppm Cd in drinking water) and/or cop− per (0.5 or 2.5 Cu mg/kg m.b., intraperitioneally, three times a week). Half of the intoxicated groups were subject− ed to physical training. The experiment was carried out over 15 weeks. Results. The training decreased the concentration of Cd in the blood and increased the concentration of zinc and copper in kidneys. The administration of metals, both alone or in combination with physical training, caused a sig− nificant decline of renal content of the sulfhydryl groups (SH groups) and a rise in the content of MDA. The high− est increase of Cd concentration was observed in untrained rats intoxicated with cadmium only. Injecting copper reduced the concentration of cadmium, but increased the oxidative processes. In trained rats intoxicated only with cadmium, the concentration of Cd in the kidney was lower, and the concentration of GSH, SH groups and the activ− ity of CAT were higher, in comparison with untrained rats. Conclusions. Physical training partially alleviates the oxidative stress induced by metals and increases the con− centration of zinc (a nutrient which protects against toxicity of Cd) in kidneys, especially in rats treated only with Cd. The combination of physical training, cadmium and a high dosage of copper, considerably intensifies the oxidative stress in the kidneys of rats (Adv Clin Exp Med 2007, 16, 4, 479–491)." @default.
• W2186352302 created "2016-06-24" @default.
• W2186352302 creator A5005588812 @default.
• W2186352302 creator A5048929467 @default.
• W2186352302 creator A5056338088 @default.
• W2186352302 creator A5061982344 @default.
• W2186352302 creator A5076126985 @default.
• W2186352302 date "2007-01-01" @default.
• W2186352302 modified "2023-09-26" @default.
• W2186352302 title "Influence of Physical Training on Level of Oxidative Damages in Kidneys of Rats Intoxicated with Cadmium as Well as Simultaneously Cadmium and Copper Wpływ treningu fizycznego na poziom uszkodzeń oksydacyjnych w nerkach szczurów intoksykowanych kadmem oraz jednocześnie kadmem i miedzią" @default.
• W2186352302 cites W1828416399 @default.
• W2186352302 cites W1871124898 @default.
• W2186352302 cites W191793640 @default.
• W2186352302 cites W1968125267 @default.
• W2186352302 cites W1972880580 @default.
• W2186352302 cites W1973278552 @default.
• W2186352302 cites W1978540552 @default.
• W2186352302 cites W1978699427 @default.
• W2186352302 cites W2001373068 @default.
• W2186352302 cites W2006370393 @default.
• W2186352302 cites W2032978536 @default.
• W2186352302 cites W2061412878 @default.
• W2186352302 cites W2076988881 @default.
• W2186352302 cites W2081745487 @default.
• W2186352302 cites W2137996875 @default.
• W2186352302 cites W2170297933 @default.
• W2186352302 hasPublicationYear "2007" @default.
• W2186352302 type Work @default.
• W2186352302 sameAs 2186352302 @default.
• W2186352302 citedByCount "0" @default.
• W2186352302 crossrefType "journal-article" @default.
• W2186352302 hasAuthorship W2186352302A5005588812 @default.
• W2186352302 hasAuthorship W2186352302A5048929467 @default.
• W2186352302 hasAuthorship W2186352302A5056338088 @default.
• W2186352302 hasAuthorship W2186352302A5061982344 @default.
• W2186352302 hasAuthorship W2186352302A5076126985 @default.
• W2186352302 hasConcept C126322002 @default.
• W2186352302 hasConcept C134018914 @default.
• W2186352302 hasConcept C140793950 @default.
• W2186352302 hasConcept C178790620 @default.
• W2186352302 hasConcept C181199279 @default.
• W2186352302 hasConcept C185592680 @default.
• W2186352302 hasConcept C2775838275 @default.
• W2186352302 hasConcept C2776151105 @default.
• W2186352302 hasConcept C2778004101 @default.
• W2186352302 hasConcept C2778760513 @default.
• W2186352302 hasConcept C2778979269 @default.
• W2186352302 hasConcept C535196362 @default.
• W2186352302 hasConcept C538909803 @default.
• W2186352302 hasConcept C544657597 @default.
• W2186352302 hasConcept C544778455 @default.
• W2186352302 hasConcept C55493867 @default.
• W2186352302 hasConcept C71924100 @default.
• W2186352302 hasConcept C86803240 @default.
• W2186352302 hasConceptScore W2186352302C126322002 @default.
• W2186352302 hasConceptScore W2186352302C134018914 @default.
• W2186352302 hasConceptScore W2186352302C140793950 @default.
• W2186352302 hasConceptScore W2186352302C178790620 @default.
• W2186352302 hasConceptScore W2186352302C181199279 @default.
• W2186352302 hasConceptScore W2186352302C185592680 @default.
• W2186352302 hasConceptScore W2186352302C2775838275 @default.
• W2186352302 hasConceptScore W2186352302C2776151105 @default.
• W2186352302 hasConceptScore W2186352302C2778004101 @default.
• W2186352302 hasConceptScore W2186352302C2778760513 @default.
• W2186352302 hasConceptScore W2186352302C2778979269 @default.
• W2186352302 hasConceptScore W2186352302C535196362 @default.
• W2186352302 hasConceptScore W2186352302C538909803 @default.
• W2186352302 hasConceptScore W2186352302C544657597 @default.
• W2186352302 hasConceptScore W2186352302C544778455 @default.
• W2186352302 hasConceptScore W2186352302C55493867 @default.
• W2186352302 hasConceptScore W2186352302C71924100 @default.
• W2186352302 hasConceptScore W2186352302C86803240 @default.
• W2186352302 hasLocation W21863523021 @default.
• W2186352302 hasOpenAccess W2186352302 @default.
• W2186352302 hasPrimaryLocation W21863523021 @default.
• W2186352302 hasRelatedWork W1966329027 @default.
• W2186352302 hasRelatedWork W1976902896 @default.
• W2186352302 hasRelatedWork W1979824498 @default.
• W2186352302 hasRelatedWork W1993141225 @default.
• W2186352302 hasRelatedWork W2002907651 @default.
• W2186352302 hasRelatedWork W2017292503 @default.
• W2186352302 hasRelatedWork W2106340240 @default.
• W2186352302 hasRelatedWork W2107270672 @default.
• W2186352302 hasRelatedWork W2116855495 @default.
• W2186352302 hasRelatedWork W2350543926 @default.
• W2186352302 hasRelatedWork W2371289635 @default.
• W2186352302 hasRelatedWork W2385369484 @default.
• W2186352302 hasRelatedWork W2400069674 @default.
• W2186352302 hasRelatedWork W25250997 @default.
• W2186352302 hasRelatedWork W2574292666 @default.
• W2186352302 hasRelatedWork W2706145310 @default.
• W2186352302 hasRelatedWork W2809708312 @default.
• W2186352302 hasRelatedWork W2946246451 @default.
• W2186352302 hasRelatedWork W3096829827 @default.
• W2186352302 hasRelatedWork W3097601489 @default.
• W2186352302 isParatext "false" @default.
• W2186352302 isRetracted "false" @default.
• W2186352302 magId "2186352302" @default.
• W2186352302 workType "article" @default.