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- W2186422866 abstract "The tonometric methodof detecting decreased gutitramucosal pH(pH)isbased onthefactthatcarbondioxide candiffuse through thewallofthesilastic balloon of thetonometer. By usingdeoxified saline andmeasuring Po2aswellasPco2this studyaimedtofollow changes inmucosal P02andrelate themtochanges inpHiin peritonitis versushaemorrhage. Twenty five pigswereused.Fivewerecontrols, in 10peritonitis wasinduced bytheinstillationoffaeces intheabdominal cavity, and 10werebled, halfofthemstepwise during threehours,andhalfofthemrapidly downtoamean (SEM)arterial pressure of30(10) mm Hg.ThedropinpHicorrelatedwellwithdecreasing intraluminal Po2(r=0.63 (0-13)) inhaemorrhage. In peritonitis thisdropoccurred withina verylimited changeinintraluminal Po2 (r=0.06(0.17)). Thusoxygenseemedtobe present inthemucosaatthesametimeas there weresigns ofanaerobic metabolism asevidenced bya lowintramucosal pH. Impaired oxygenextraction orutilisation, orboth, isproposed asanexplanation to thisseemingly paradoxical situation. (Gut 1995; 37:791-797)" @default.
- W2186422866 created "2016-06-24" @default.
- W2186422866 creator A5037411357 @default.
- W2186422866 creator A5085817145 @default.
- W2186422866 date "1995-01-01" @default.
- W2186422866 modified "2023-09-24" @default.
- W2186422866 title "Gutintramucosal pHandintraluminal Po2ina porcine modelofperitonitis orhaemorrhage" @default.
- W2186422866 cites W2079740726 @default.
- W2186422866 cites W2416031661 @default.
- W2186422866 hasPublicationYear "1995" @default.
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