Matches in SemOpenAlex for { <https://semopenalex.org/work/W2186435979> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2186435979 endingPage "651" @default.
- W2186435979 startingPage "649" @default.
- W2186435979 abstract "Objective : Many therapeutic drugs used for the treatment of Alzheimer’s disease are acetylcholinesterase inhibitors. This work was carried out to find out the acetylcholinesterase inhibitory properties of the withanolides of Datura metel . Method : We used modified in vitro assay method of Ellman using acetylcholinesterase from Electropus electricus (electric eel). Methanolic extract of D. metel particularly the withanolide rich fraction of the extract inhibited acetylcholinesterase in a dose dependent manner. Results : Four withanolides e.g. 12-deoxywithastramonolide [IC 50 value = 4.6 ± 0.27 (9.775µM)], lycium substance B [IC 50 value = 13.61 ± 0.18 (29.978 µM)], withametelin [IC 50 value = 21.03 ± 0.51 (48.234 µM)], secowithametelin [IC 50 value = 22.97 ± 0.06 (45.039 µM)], had acetylcholinesterase inhibitory property. Conclusion : The results suggest that the acetylcholinesterase inhibitory property of D. metel is due to the presence of these withanolides." @default.
- W2186435979 created "2016-06-24" @default.
- W2186435979 creator A5066714490 @default.
- W2186435979 creator A5069952097 @default.
- W2186435979 date "2014-01-01" @default.
- W2186435979 modified "2023-09-28" @default.
- W2186435979 title "ACETYLCHOLINESTERASE INHIBITORY PROPERTY OF DATURA METEL L. WITHANOLIDES" @default.
- W2186435979 cites W1964228070 @default.
- W2186435979 cites W1964907828 @default.
- W2186435979 cites W1971048984 @default.
- W2186435979 cites W1974330500 @default.
- W2186435979 cites W1982232143 @default.
- W2186435979 cites W1984841807 @default.
- W2186435979 cites W1996811872 @default.
- W2186435979 cites W2009303078 @default.
- W2186435979 cites W2009994623 @default.
- W2186435979 cites W2017645489 @default.
- W2186435979 cites W2019235852 @default.
- W2186435979 cites W2021600498 @default.
- W2186435979 cites W2027751612 @default.
- W2186435979 cites W2030333474 @default.
- W2186435979 cites W2049763771 @default.
- W2186435979 cites W2053340980 @default.
- W2186435979 cites W2059604657 @default.
- W2186435979 cites W2063302846 @default.
- W2186435979 cites W2103688571 @default.
- W2186435979 cites W2105805458 @default.
- W2186435979 cites W2118346486 @default.
- W2186435979 cites W2133897064 @default.
- W2186435979 cites W2156606951 @default.
- W2186435979 cites W2208970852 @default.
- W2186435979 hasPublicationYear "2014" @default.
- W2186435979 type Work @default.
- W2186435979 sameAs 2186435979 @default.
- W2186435979 citedByCount "0" @default.
- W2186435979 crossrefType "journal-article" @default.
- W2186435979 hasAuthorship W2186435979A5066714490 @default.
- W2186435979 hasAuthorship W2186435979A5069952097 @default.
- W2186435979 hasConcept C142724271 @default.
- W2186435979 hasConcept C169760540 @default.
- W2186435979 hasConcept C17077164 @default.
- W2186435979 hasConcept C181199279 @default.
- W2186435979 hasConcept C185592680 @default.
- W2186435979 hasConcept C204787440 @default.
- W2186435979 hasConcept C2778378431 @default.
- W2186435979 hasConcept C2778816929 @default.
- W2186435979 hasConcept C2780069950 @default.
- W2186435979 hasConcept C55493867 @default.
- W2186435979 hasConcept C556039675 @default.
- W2186435979 hasConcept C71240020 @default.
- W2186435979 hasConcept C71924100 @default.
- W2186435979 hasConcept C86803240 @default.
- W2186435979 hasConceptScore W2186435979C142724271 @default.
- W2186435979 hasConceptScore W2186435979C169760540 @default.
- W2186435979 hasConceptScore W2186435979C17077164 @default.
- W2186435979 hasConceptScore W2186435979C181199279 @default.
- W2186435979 hasConceptScore W2186435979C185592680 @default.
- W2186435979 hasConceptScore W2186435979C204787440 @default.
- W2186435979 hasConceptScore W2186435979C2778378431 @default.
- W2186435979 hasConceptScore W2186435979C2778816929 @default.
- W2186435979 hasConceptScore W2186435979C2780069950 @default.
- W2186435979 hasConceptScore W2186435979C55493867 @default.
- W2186435979 hasConceptScore W2186435979C556039675 @default.
- W2186435979 hasConceptScore W2186435979C71240020 @default.
- W2186435979 hasConceptScore W2186435979C71924100 @default.
- W2186435979 hasConceptScore W2186435979C86803240 @default.
- W2186435979 hasIssue "4" @default.
- W2186435979 hasLocation W21864359791 @default.
- W2186435979 hasOpenAccess W2186435979 @default.
- W2186435979 hasPrimaryLocation W21864359791 @default.
- W2186435979 hasRelatedWork W2000032271 @default.
- W2186435979 hasRelatedWork W2011831683 @default.
- W2186435979 hasRelatedWork W2034863319 @default.
- W2186435979 hasRelatedWork W2060175251 @default.
- W2186435979 hasRelatedWork W2079124171 @default.
- W2186435979 hasRelatedWork W2087419529 @default.
- W2186435979 hasRelatedWork W2100033271 @default.
- W2186435979 hasRelatedWork W2134832655 @default.
- W2186435979 hasRelatedWork W2189877827 @default.
- W2186435979 hasRelatedWork W2348030390 @default.
- W2186435979 hasRelatedWork W2478821724 @default.
- W2186435979 hasRelatedWork W2590442802 @default.
- W2186435979 hasRelatedWork W2759969378 @default.
- W2186435979 hasRelatedWork W2900209181 @default.
- W2186435979 hasRelatedWork W2986325516 @default.
- W2186435979 hasRelatedWork W3023817552 @default.
- W2186435979 hasRelatedWork W3043314745 @default.
- W2186435979 hasRelatedWork W3044013316 @default.
- W2186435979 hasRelatedWork W3084039304 @default.
- W2186435979 hasRelatedWork W3164471634 @default.
- W2186435979 hasVolume "6" @default.
- W2186435979 isParatext "false" @default.
- W2186435979 isRetracted "false" @default.
- W2186435979 magId "2186435979" @default.
- W2186435979 workType "article" @default.