Matches in SemOpenAlex for { <https://semopenalex.org/work/W2186440110> ?p ?o ?g. }
- W2186440110 endingPage "11343" @default.
- W2186440110 startingPage "11343" @default.
- W2186440110 abstract "Crohn's disease and ulcerative colitis are two important categories of human inflammatory bowel disease (IBD). Because the precise mechanisms of the inflammation and immune responses in IBD have not been fully elucidated, the treatment of IBD primarily aims to inhibit the pathogenic factors of the inflammatory cascade. Inconsistencies exist regarding the response and side effects of the drugs that are currently used to treat IBD. Recent studies have suggested that the use of nanomedicine might be advantageous for the treatment of intestinal inflammation because nano-sized molecules can effectively penetrate epithelial and inflammatory cells. We reviewed nanomedicine treatments, such as the use of small interfering RNAs, antisense oligonucleotides, and anti-inflammatory molecules with delivery systems in experimental colitis models and clinical trials for IBD based on a systematic search. The efficacy and usefulness of the treatments reviewed in this manuscript have been demonstrated in experimental colitis models and clinical trials using various types of nanomedicine. Nanomedicine is expected to become a new therapeutic approach to the treatment of IBD." @default.
- W2186440110 created "2016-06-24" @default.
- W2186440110 creator A5013194037 @default.
- W2186440110 creator A5065128587 @default.
- W2186440110 creator A5066245880 @default.
- W2186440110 date "2015-01-01" @default.
- W2186440110 modified "2023-09-26" @default.
- W2186440110 title "Nanomedicine and drug delivery strategies for treatment of inflammatory bowel disease" @default.
- W2186440110 cites W1485526722 @default.
- W2186440110 cites W1572221909 @default.
- W2186440110 cites W1587849076 @default.
- W2186440110 cites W1663371441 @default.
- W2186440110 cites W1826915530 @default.
- W2186440110 cites W1897551156 @default.
- W2186440110 cites W1930389691 @default.
- W2186440110 cites W1931329582 @default.
- W2186440110 cites W1969382880 @default.
- W2186440110 cites W1972630955 @default.
- W2186440110 cites W1980988152 @default.
- W2186440110 cites W1982829846 @default.
- W2186440110 cites W1983877655 @default.
- W2186440110 cites W1985562806 @default.
- W2186440110 cites W1985744874 @default.
- W2186440110 cites W1986242902 @default.
- W2186440110 cites W1986658197 @default.
- W2186440110 cites W1988658785 @default.
- W2186440110 cites W1991140433 @default.
- W2186440110 cites W1992529637 @default.
- W2186440110 cites W1993239608 @default.
- W2186440110 cites W1994720283 @default.
- W2186440110 cites W1996011312 @default.
- W2186440110 cites W1997888176 @default.
- W2186440110 cites W1999686085 @default.
- W2186440110 cites W1999732094 @default.
- W2186440110 cites W1999855196 @default.
- W2186440110 cites W2002780176 @default.
- W2186440110 cites W2002785080 @default.
- W2186440110 cites W2009025779 @default.
- W2186440110 cites W2011110543 @default.
- W2186440110 cites W2011905672 @default.
- W2186440110 cites W2019886362 @default.
- W2186440110 cites W2026058763 @default.
- W2186440110 cites W2027556747 @default.
- W2186440110 cites W2028402416 @default.
- W2186440110 cites W2032175829 @default.
- W2186440110 cites W2036242475 @default.
- W2186440110 cites W2038535814 @default.
- W2186440110 cites W2043620021 @default.
- W2186440110 cites W2050617797 @default.
- W2186440110 cites W2057387637 @default.
- W2186440110 cites W2059498854 @default.
- W2186440110 cites W2059535343 @default.
- W2186440110 cites W2060056553 @default.
- W2186440110 cites W2061092005 @default.
- W2186440110 cites W2064808830 @default.
- W2186440110 cites W2066496851 @default.
- W2186440110 cites W2068885672 @default.
- W2186440110 cites W2078339059 @default.
- W2186440110 cites W2078621117 @default.
- W2186440110 cites W2080275691 @default.
- W2186440110 cites W2081601920 @default.
- W2186440110 cites W2083323027 @default.
- W2186440110 cites W2087843844 @default.
- W2186440110 cites W2092643186 @default.
- W2186440110 cites W2093119133 @default.
- W2186440110 cites W2096619153 @default.
- W2186440110 cites W2099074761 @default.
- W2186440110 cites W2105409124 @default.
- W2186440110 cites W2106476912 @default.
- W2186440110 cites W2112082141 @default.
- W2186440110 cites W2112340015 @default.
- W2186440110 cites W2112981618 @default.
- W2186440110 cites W2113591882 @default.
- W2186440110 cites W2116185627 @default.
- W2186440110 cites W2118042314 @default.
- W2186440110 cites W2128890061 @default.
- W2186440110 cites W2129855398 @default.
- W2186440110 cites W2133226723 @default.
- W2186440110 cites W2135566609 @default.
- W2186440110 cites W2144331651 @default.
- W2186440110 cites W2149109920 @default.
- W2186440110 cites W2150176853 @default.
- W2186440110 cites W2152429732 @default.
- W2186440110 cites W2255911290 @default.
- W2186440110 cites W2321453230 @default.
- W2186440110 cites W2399215718 @default.
- W2186440110 cites W2416841626 @default.
- W2186440110 cites W4292198229 @default.
- W2186440110 doi "https://doi.org/10.3748/wjg.v21.i40.11343" @default.
- W2186440110 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4616210" @default.
- W2186440110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26525603" @default.
- W2186440110 hasPublicationYear "2015" @default.
- W2186440110 type Work @default.
- W2186440110 sameAs 2186440110 @default.
- W2186440110 citedByCount "38" @default.
- W2186440110 countsByYear W21864401102016 @default.
- W2186440110 countsByYear W21864401102017 @default.
- W2186440110 countsByYear W21864401102018 @default.