Matches in SemOpenAlex for { <https://semopenalex.org/work/W2186510265> ?p ?o ?g. }
- W2186510265 endingPage "35" @default.
- W2186510265 startingPage "27" @default.
- W2186510265 abstract "Synthetic neural scaffolds hold promise to eventually replace nerve autografts for tissue repair following peripheral nerve injury. Despite substantial evidence for the influence of scaffold geometry and dimensions on the rate of axonal growth, systematic evaluation of these parameters remains a challenge due to limitations in materials processing. We have employed fiber drawing to engineer a wide spectrum of polymer-based neural scaffolds with varied geometries and core sizes. Using isolated whole dorsal root ganglia as an in vitro model system we have identified key features enhancing nerve growth within these fiber scaffolds. Our approach enabled straightforward integration of microscopic topography at the scale of nerve fascicles within the scaffold cores, which led to accelerated Schwann cell migration, as well as neurite growth and alignment. Our findings indicate that fiber drawing provides a scalable and versatile strategy for producing nerve guidance channels capable of controlling direction and accelerating the rate of axonal growth." @default.
- W2186510265 created "2016-06-24" @default.
- W2186510265 creator A5008804140 @default.
- W2186510265 creator A5009393709 @default.
- W2186510265 creator A5009750653 @default.
- W2186510265 creator A5019942717 @default.
- W2186510265 creator A5031487602 @default.
- W2186510265 creator A5057078729 @default.
- W2186510265 creator A5063929633 @default.
- W2186510265 creator A5087279006 @default.
- W2186510265 date "2016-03-01" @default.
- W2186510265 modified "2023-10-17" @default.
- W2186510265 title "Thermally drawn fibers as nerve guidance scaffolds" @default.
- W2186510265 cites W1409037628 @default.
- W2186510265 cites W1789881463 @default.
- W2186510265 cites W1846801464 @default.
- W2186510265 cites W1942914657 @default.
- W2186510265 cites W1967941655 @default.
- W2186510265 cites W1969020388 @default.
- W2186510265 cites W1971963621 @default.
- W2186510265 cites W1972837041 @default.
- W2186510265 cites W1978170588 @default.
- W2186510265 cites W1979042657 @default.
- W2186510265 cites W1984810729 @default.
- W2186510265 cites W1988447637 @default.
- W2186510265 cites W1996069588 @default.
- W2186510265 cites W2001384439 @default.
- W2186510265 cites W2011780078 @default.
- W2186510265 cites W2012100020 @default.
- W2186510265 cites W2019770939 @default.
- W2186510265 cites W2020233463 @default.
- W2186510265 cites W2022058531 @default.
- W2186510265 cites W2024405375 @default.
- W2186510265 cites W2024856592 @default.
- W2186510265 cites W2027323198 @default.
- W2186510265 cites W2027531870 @default.
- W2186510265 cites W2027611318 @default.
- W2186510265 cites W2036297747 @default.
- W2186510265 cites W2037769225 @default.
- W2186510265 cites W2052424792 @default.
- W2186510265 cites W2054410626 @default.
- W2186510265 cites W2055432244 @default.
- W2186510265 cites W2056859189 @default.
- W2186510265 cites W2057358727 @default.
- W2186510265 cites W2067570071 @default.
- W2186510265 cites W2073193146 @default.
- W2186510265 cites W2079133664 @default.
- W2186510265 cites W2083566918 @default.
- W2186510265 cites W2086276924 @default.
- W2186510265 cites W2087776156 @default.
- W2186510265 cites W2088418016 @default.
- W2186510265 cites W2094644814 @default.
- W2186510265 cites W2102625278 @default.
- W2186510265 cites W2107514110 @default.
- W2186510265 cites W2120002445 @default.
- W2186510265 cites W2139997147 @default.
- W2186510265 cites W2142254746 @default.
- W2186510265 cites W2144349786 @default.
- W2186510265 cites W2146646098 @default.
- W2186510265 cites W2152551605 @default.
- W2186510265 cites W2156229286 @default.
- W2186510265 cites W2157281893 @default.
- W2186510265 cites W2167986300 @default.
- W2186510265 cites W2172086451 @default.
- W2186510265 cites W2248910938 @default.
- W2186510265 cites W31779581 @default.
- W2186510265 cites W4213263913 @default.
- W2186510265 doi "https://doi.org/10.1016/j.biomaterials.2015.11.063" @default.
- W2186510265 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5134911" @default.
- W2186510265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26717246" @default.
- W2186510265 hasPublicationYear "2016" @default.
- W2186510265 type Work @default.
- W2186510265 sameAs 2186510265 @default.
- W2186510265 citedByCount "58" @default.
- W2186510265 countsByYear W21865102652016 @default.
- W2186510265 countsByYear W21865102652017 @default.
- W2186510265 countsByYear W21865102652018 @default.
- W2186510265 countsByYear W21865102652019 @default.
- W2186510265 countsByYear W21865102652020 @default.
- W2186510265 countsByYear W21865102652021 @default.
- W2186510265 countsByYear W21865102652022 @default.
- W2186510265 countsByYear W21865102652023 @default.
- W2186510265 crossrefType "journal-article" @default.
- W2186510265 hasAuthorship W2186510265A5008804140 @default.
- W2186510265 hasAuthorship W2186510265A5009393709 @default.
- W2186510265 hasAuthorship W2186510265A5009750653 @default.
- W2186510265 hasAuthorship W2186510265A5019942717 @default.
- W2186510265 hasAuthorship W2186510265A5031487602 @default.
- W2186510265 hasAuthorship W2186510265A5057078729 @default.
- W2186510265 hasAuthorship W2186510265A5063929633 @default.
- W2186510265 hasAuthorship W2186510265A5087279006 @default.
- W2186510265 hasBestOaLocation W21865102652 @default.
- W2186510265 hasConcept C105702510 @default.
- W2186510265 hasConcept C113246987 @default.
- W2186510265 hasConcept C136229726 @default.
- W2186510265 hasConcept C140530291 @default.
- W2186510265 hasConcept C169760540 @default.
- W2186510265 hasConcept C187761678 @default.