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- W2186544949 abstract "This work is focused on the development of a microsystem for the measurement of mechanical tension from resistance blood vessels. To date, the smallest vessels used for these tests are 100-120 µm in diameter, hence they do not belong to the resistance district. The current technique employs two wires which are manually inserted into the vessel. One of the wires is mechanically interfaced to a load cell. The proposed solution is the introduction of a purposely developed Silicon-based sensor. Aimed at defining the final specifications of the microsensor, first experimental tests have been performed with bigger vessels. Insulation and packaging issues have been faced for different experimental set-ups, and a preliminary methodology for a safe interaction with this biological system has been drawn out. With the proposed Silicon-based sensor, the minimum diameter of the microvessels could go down to 50 µm. The use of Silicon may also allow the integration in the same device of a chemically reactive coat for measuring concomitantly biologically active substances such as nitric oxide and carbon monoxide (dual mechanical/chemical sensor). Alternatives to the Silicon-based solution are currently under evaluation; they could represent a valid support to perform e.g. isotonic measurements and provide further relevant information to the clinicians." @default.
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- W2186544949 date "2003-01-01" @default.
- W2186544949 modified "2023-09-25" @default.
- W2186544949 title "Design of a Microsensor for the Measurement of Mechanical Tension from Resistance Blood Vessels" @default.
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