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- W2186616078 abstract "The reaction of 2-(aryloxymethyl) benzo thioamide with various substituted phenacyl bromides afforded 2-[2-(aryloxymethyl)-phenyl]-N′-[4-(aryl)-thiazol-2yl]-benzohydrazide derivatives. The benzothiamide is prepared from corresponding hydrazide in KSCN/HCl in methanol. Substituted thiazolo-[3,2-b]-[1,2,4]-triazole derivatives were synthesized by a condensation reaction of the one pot three component reaction of substituted aromatic aldehydes and monochloroacetic acid in acetic acid in the presence of acetic anhydride and anhydrous sodium acetate with 5-{2-[(aryloxymethyl)-methyl]-phenyl}-4H-[1,2,4]-triazole-3-thiol. All structures of the newly synthesized compounds were elucidated by elemental analysis and spectral data. The new compounds have been tested for their in vitro antimicrobial activities. However, they shown moderate to good antimicrobial activity. Among the tested compounds 3h, and 5d shown significant antibacterial activity while 3d, 3h and 5d shown significant antifungal activity." @default.
- W2186616078 created "2016-06-24" @default.
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- W2186616078 date "2015-01-01" @default.
- W2186616078 modified "2023-09-28" @default.
- W2186616078 title "Synthesis, Characterization and Antimicrobial Activities of Some Novel Thiazoles and Thiazolo-(3,2-b)-(1,2,4)-triazole Derivatives" @default.
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- W2186616078 hasPublicationYear "2015" @default.
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