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- W2186686452 abstract "Immunology is one of the most rapidly developing areas of medical biotechnology research and has great promises with regard to the prevention and treatment of a wide range of disorders such as the inflammatory diseases of skin, gut, respiratory tract, joints and central organs. In addition, infectious diseases are now primarily considered immunological disorders, while neoplastic diseases and organ transplantation and several autoimmune diseases are involved in an immunosuppressive state. Immunomodulators are natural or synthetic substances that help regulate or normalize the immune system. Immunomodulators correct immune systems that are out of balance. Natural immunomodulators are less potent than prescription immunomodulators and also less likely to cause side effects. Prescription synthetic immunomodulator medications, such as azathioprine, 6-mercaptopurine, methotrexate, and mycophenolate mofetil, work by suppressing the immune system and decreasing inflammation in the digestive tract in people with inflammatory bowel disease, ulcerative colitis, and Crohn's disease. The benefits of immunomodulators stem from their ability to stimulate natural and adaptive defense mechanisms, such as cytokines, which enables the body to help itself. There are two types of immunomodulators: immunosuppressants and immunostimulants. Immunosuppressants are the agents which suppress the immune system and are used for the control of pathological immune response in autoimmune disease, graft rejection etc. Immunostimulants are the agents which are envisaged to enhance body's resistance against infections; they enhance the basal levels of immune response, and in individuals with impairment of immune response as immunotherapeutic agent. A number of disorders such as immunodeficiency state, autoimmune disease, cancer and viral infection can be treated with immunostimulants drugs. Immunomodulators are becoming a viable adjunct to established modalities offering a novel approach for the treatment of infectious disease in the coming decades of 21 st century" @default.
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- W2186686452 date "2012-01-01" @default.
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- W2186686452 title "IMMUNOMODULATORS: A PHARMACOLOGICAL REVIEW" @default.
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