Matches in SemOpenAlex for { <https://semopenalex.org/work/W2186815749> ?p ?o ?g. }
- W2186815749 endingPage "9" @default.
- W2186815749 startingPage "1923" @default.
- W2186815749 abstract "In this study, the preparation and in vitro characterisation of metformin HCl-loaded CS-PLGA nanoparticles (NPs) were aimed. The prepared nanoparticles (blank nanoparticles (C-1), 50 mg of metformin HCl loaded nanoparticles (C-2) and 75 mg of metformin HCl loaded nanoparticles (C-3) ranged in size from 506.67±13.61 to 516.33±16.85 nm and had surface charges of 22.57±1.21 to 32.37±0.57 mV. Low encapsulation efficiency was observed for both nanoparticle formulations due to the leakage of metformin HCl to the external medium during preparation of nanoparticles. Nanoparticle formulations showed highly reproducible drug release profiles. ~20% of metformin HCl was released within 30 minutes and approximately 98% of the loaded metformin HCl was released at 144 hours in a phosphate buffer (PB; pH 6.8). No statistically significant difference was noted between the in vitro release profiles of the nanoparticles (C-2 and C-3) containing metformin HCl. Also, nanoparticles were characterised using FT-IR and DSC." @default.
- W2186815749 created "2016-06-24" @default.
- W2186815749 creator A5021026398 @default.
- W2186815749 creator A5076869891 @default.
- W2186815749 date "2014-11-01" @default.
- W2186815749 modified "2023-09-23" @default.
- W2186815749 title "Chitosan-poly (lactide-co-glycolide) (CS-PLGA) nanoparticles containing metformin HCl: preparation and in vitro evaluation." @default.
- W2186815749 cites W1680236584 @default.
- W2186815749 cites W1682768769 @default.
- W2186815749 cites W1729582545 @default.
- W2186815749 cites W1982096781 @default.
- W2186815749 cites W1993999157 @default.
- W2186815749 cites W1995258988 @default.
- W2186815749 cites W2004687835 @default.
- W2186815749 cites W2004759520 @default.
- W2186815749 cites W2005327657 @default.
- W2186815749 cites W2012025047 @default.
- W2186815749 cites W2022093158 @default.
- W2186815749 cites W2023687860 @default.
- W2186815749 cites W2035599707 @default.
- W2186815749 cites W2038864652 @default.
- W2186815749 cites W2055249407 @default.
- W2186815749 cites W2057876241 @default.
- W2186815749 cites W2059862524 @default.
- W2186815749 cites W2060536308 @default.
- W2186815749 cites W2062476487 @default.
- W2186815749 cites W2067428788 @default.
- W2186815749 cites W2070040259 @default.
- W2186815749 cites W2074561945 @default.
- W2186815749 cites W2076925826 @default.
- W2186815749 cites W2080068505 @default.
- W2186815749 cites W2087032263 @default.
- W2186815749 cites W2087543170 @default.
- W2186815749 cites W2095300073 @default.
- W2186815749 cites W2119942076 @default.
- W2186815749 cites W2138375768 @default.
- W2186815749 cites W2148224419 @default.
- W2186815749 cites W2154043786 @default.
- W2186815749 cites W2159872953 @default.
- W2186815749 cites W2163565101 @default.
- W2186815749 cites W2165164186 @default.
- W2186815749 cites W2209638 @default.
- W2186815749 cites W2483774597 @default.
- W2186815749 cites W2495553460 @default.
- W2186815749 cites W71540099 @default.
- W2186815749 cites W2337176391 @default.
- W2186815749 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25362616" @default.
- W2186815749 hasPublicationYear "2014" @default.
- W2186815749 type Work @default.
- W2186815749 sameAs 2186815749 @default.
- W2186815749 citedByCount "6" @default.
- W2186815749 countsByYear W21868157492017 @default.
- W2186815749 countsByYear W21868157492019 @default.
- W2186815749 countsByYear W21868157492020 @default.
- W2186815749 countsByYear W21868157492021 @default.
- W2186815749 countsByYear W21868157492022 @default.
- W2186815749 crossrefType "journal-article" @default.
- W2186815749 hasAuthorship W2186815749A5021026398 @default.
- W2186815749 hasAuthorship W2186815749A5076869891 @default.
- W2186815749 hasConcept C134018914 @default.
- W2186815749 hasConcept C13965031 @default.
- W2186815749 hasConcept C155672457 @default.
- W2186815749 hasConcept C171250308 @default.
- W2186815749 hasConcept C178790620 @default.
- W2186815749 hasConcept C185592680 @default.
- W2186815749 hasConcept C192562407 @default.
- W2186815749 hasConcept C202751555 @default.
- W2186815749 hasConcept C2779306644 @default.
- W2186815749 hasConcept C2779732960 @default.
- W2186815749 hasConcept C2780165375 @default.
- W2186815749 hasConcept C2780323712 @default.
- W2186815749 hasConcept C43617362 @default.
- W2186815749 hasConcept C55493867 @default.
- W2186815749 hasConcept C71924100 @default.
- W2186815749 hasConcept C96616956 @default.
- W2186815749 hasConceptScore W2186815749C134018914 @default.
- W2186815749 hasConceptScore W2186815749C13965031 @default.
- W2186815749 hasConceptScore W2186815749C155672457 @default.
- W2186815749 hasConceptScore W2186815749C171250308 @default.
- W2186815749 hasConceptScore W2186815749C178790620 @default.
- W2186815749 hasConceptScore W2186815749C185592680 @default.
- W2186815749 hasConceptScore W2186815749C192562407 @default.
- W2186815749 hasConceptScore W2186815749C202751555 @default.
- W2186815749 hasConceptScore W2186815749C2779306644 @default.
- W2186815749 hasConceptScore W2186815749C2779732960 @default.
- W2186815749 hasConceptScore W2186815749C2780165375 @default.
- W2186815749 hasConceptScore W2186815749C2780323712 @default.
- W2186815749 hasConceptScore W2186815749C43617362 @default.
- W2186815749 hasConceptScore W2186815749C55493867 @default.
- W2186815749 hasConceptScore W2186815749C71924100 @default.
- W2186815749 hasConceptScore W2186815749C96616956 @default.
- W2186815749 hasIssue "6" @default.
- W2186815749 hasLocation W21868157491 @default.
- W2186815749 hasOpenAccess W2186815749 @default.
- W2186815749 hasPrimaryLocation W21868157491 @default.
- W2186815749 hasRelatedWork W1964217657 @default.
- W2186815749 hasRelatedWork W2038940441 @default.
- W2186815749 hasRelatedWork W2039390235 @default.