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- W2186860986 abstract "In recent past pesticide poisoning and related diseases have gained considerable attention. Cyfluthrin is a type II synthetic pyrethroid pesticide. Its versatility makes it a useful active ingredient in the manufacturing of many pesticides. In the present study cyfluthrin has been evaluated for its acute hepatotoxicity in Swiss albino mice. For acute hepatotoxicity acute low (0.32 µg/kg b.wt), acute medium (0.64 µg/kg b.wt) and acute high (1.28 µg/kg b.wt) doses of cyfluthrin were orally administered once daily for 30 consecutive days and mice were necropsied after 30 days of treatment. Biochemical estimations of ALP, SGPT, and SGOT together with histopathological studies were carried out. Acute treatment of cyfluthrin for 30 days resulted in significant increase in liver weight (p<0.05). Significant increase in activity of ALP, SGPT and SGOT (p<0.001) levels were also observed. A variety of pathological lesions in liver were observed in acute treatment. In conclusion present results suggest that cyfluthrin is hepatotoxic to Swiss albino mice." @default.
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- W2186860986 date "2012-01-01" @default.
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- W2186860986 title "Effects of Cyfluthrin on Biochemical and Histopathological Alterations in Liver of Swiss Albino Mice" @default.
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