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- W2186866413 abstract "We present a microfluidic chip for high-throughput PDT screening with the capability of individual controls on light exposure dose, pericellular oxygen level and photosensitizer concentration. Both oxygen and photosensitizer gradients are produced by microfluidic gradient-generating networks and imposed on target cells. Various photo-exposures are provided by orthogonally stacking the two layers of gray scale liquid filters. All three parameters are independently controlled in the microfluidic channels monolithically integrated in a single chip. Using this platform, we successfully demonstrated the PDT efficacy on cancer cells for different exposure doses, oxygen levels and photosensitizer concentrations." @default.
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- W2186866413 date "2010-01-01" @default.
- W2186866413 modified "2023-09-28" @default.
- W2186866413 title "HIGH-THROUGHPUT OF PHOTODYNAMIC THERAPY (PDT) SCREENING FROM MULTIPLE PARAMETER ASSAYS OF 1,000 DIFFERENT CONDITIONS IN A SINGLE CHIP" @default.
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