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- W2186926715 abstract "The present experiment was designed to evaluate the anti-haemonchosis activities of the aqueous-methanolic extracts rhizome of Curcuma (C) longa (P1), fruit of Citrullus (Ct) colocynthis (P2) and seed of Peganum (P)harmala (P3). The formulations consisting of a combination of three plants exhibited highest anthelmintic activity in a dose dependent manner and all the worms were found dead 4 hr post-exposure at the dose rate of 100 mg/ml. Mortality of worms was comparable to that levamisole at 1.50 mg/ml after 2 hours post-exposure. There was no mortality of worms in PBS till 12 hours. In vivo, efficacy of the study plants were determined using faecal eggs count reduction test in sheep naturally infected with mixed species of nematodes. The maximum reduction (98.7%) in EPG of faeces was recorded on day 18 post-treatment in sheep treated with th combination of three plants at the dose rate of 4 gm/kg body weight. The reduction in EPG (99.4%) with levamisole was comparable to that with herbal extract at the dose rate of 4 gm/kg body weight as mentioned. Therefore, HT seems to be promising as an anthelmintic for animals. Large scale trials on efficacy and safety however, are recommended before the HT studies are considered for commercialization." @default.
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- W2186926715 date "2013-01-01" @default.
- W2186926715 modified "2023-09-22" @default.
- W2186926715 title "Comparative Anthelmintic Efficacy of Curcuma longa, Citrullus colocynthis and Peganum harmala" @default.
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