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• W2186951021 abstract "As the rate of AIDS - related mortality continues to decrease due to advanced combination antiretroviral therapies available, many recent efforts h ave been made to stop n ew infections. While there are still ongoing research efforts on HIV vaccine development, Truvada ® for pre - exposure prophylaxis (PrEP) is available to general public as an HIV prevention strategy. PrEP specifically targets populations at - risk including gay men, men - who - have - sex - with - men(MSM), and heterosexual serodiscordant couples. A recent study of PrEP utilization reported an extraordinary slow uptake o f PrEP; it suggests a need to evaluate current PrEP roll - out. This review explores potential causes of the current slow uptake phenomena. These include common concerns among PrEP providers and populations at - risk; long - term side effects, PrEP adherence, fear of drug - resistance, and potential rise of risky sexual behaviors. Previous PrEP randomized clinical trials (RCTs) showed its effectiveness but did not recognize its potential barriers outside clinical settings. Implementation of PrEP in a population - level should therefore include comprehensive counseling programs to support medication - adherence, and futu re research must carefully monitor current PrEP users and address potential pitfalls to maximize its protective benefits." @default.
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• W2186951021 date "2015-05-10" @default.
• W2186951021 modified "2023-10-05" @default.
• W2186951021 title "PRE-EXPOSURE PROPHYLAXIS (PREP) AS HIV PREVENTION STRATEGY AND PUBLIC HEALTH IMPLICATIONS" @default.
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• W2186951021 doi "https://doi.org/10.7897/2230-8407.06450" @default.
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