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- W2186963227 abstract "The methanol extract of Amaranthus spinosus (Amaranthaceae) stem was investigated for its antihyperglycemic and antihyperlipidaemic effects in male Wister albino rats. Diabetes was induced in the albino rats by administration of a single dose of alloxan monohydrate (150 mg/kg, i.p). The methanol extract of A. spinosus (MEAS) was administered daily at single doses of 250 and 500 mg/kg, p.o to diabetes-induced rats for a period of 15 days. The effect of MEAS on blood glucose level was measured in the diabetic rats. Serum lipid profiles [total cholesterol, triglycerides, phospholipids (low density, very low density and high density lipoprotein)] were also determined. The activities were also compared to the effect produced by a standard anti diabetic agent, glibenclamide. The present investigation established pharmacological evidence to support the folklore claim that MEAS is an anti diabetic agent." @default.
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- W2186963227 date "2010-01-01" @default.
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- W2186963227 title "Antihyperglycemic and antihyperlipidaemic activities of Amaranthus spinosus Linn extract on alloxan induced diabetic rats." @default.
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