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- W2187054388 abstract "It is well established that genetic mutations that impair BRCA1function predispose women to early onset of breast and ovariancancer. However, the co-regulatory factors that support normalBRCA1 functions remain to be identified. Using a biochemicalapproach to search for such co-regulatory factors, we identifiedhGCN5, TRRAP, and hMSH2/6 as BRCA1-interacting proteins.Genetic mutations in the C-terminal transactivation domain ofBRCA1, as found in breast cancer patients (Chapman, M. S., andVerma,I.M.(1996)" @default.
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- W2187054388 date "2006-01-01" @default.
- W2187054388 modified "2023-09-27" @default.
- W2187054388 title "An hGCN5/TRRAP Histone Acetyltransferase Complex Co-activates BRCA1 Transactivation Function through" @default.
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- W2187054388 hasPublicationYear "2006" @default.
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