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- W2187125024 abstract "Reactive oxygen species (ROS) causes the oxidative damage to biological macromolecules like DNA which leads to the generation of cancer and other chronic diseases. Dietary antioxidants are known to prevent the oxidative damage. In this study, antioxidant rich dietary sources in leaves and flowers of Spathodea campanulata are used to prevent the DNA damage induced by t‐Butyl hydroperoxide and hydrogen peroxide. The antioxidants present in the ethanol extract of leaves and flowers of Spathodea campanulata prevent the DNA damage very effectively. The both ethanol extracts offered protection up to 95% at 50µg concentra tion against t‐BOOH and H2O2 i nduced DNA fragmentation in agarose gel electrophoresis. Whereas the standard antioxidants like BHA showed 90% protection at 400µM concentration. Hence the combined effect of antioxidants present in the both ethanol extracts are very potent in prevention of ROS induced DNA damage." @default.
- W2187125024 created "2016-06-24" @default.
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- W2187125024 date "2011-01-01" @default.
- W2187125024 modified "2023-09-27" @default.
- W2187125024 title "ANTIOXIDANT ACTIVITY OF SPATHODEA CAMPANULATA IN PREVENTION OF TBOOH AND H2O2 INDUCED DNA DAMAGE" @default.
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