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- W2187163957 abstract "Introduction Following myocardial infarction, the extent of irreversible myocardial injury has important prognostic implications. In MRI, the delayed enhancement technique can distinguish between viable and non-viable myocardium [1]. Segmented inversion recovery turbo FLASH (IRTFL) has been shown to give the best contrast between viable and infarcted myocardium [2]. However, the segmentation technique requires breathholding and a regular RR interval for good image quality. Single shot inversion recovery trueFISP (IR-trueFISP) gives good image quality independent of heart rate variation [3] but complete nulling of normal myocardium is difficult due to the long acquisition window, resulting in reduced contrast between normal and infarcted myocardium. The TI scouting method [4] requires multiple heart beats. A MR infarct imaging technique insensitive to both TI and RR interval is highly desirable for arrhythmic patients. Purpose To design an arrhythmia and TI insensitive sequence on a clinical MRI scanner equipped with high performance, state of the art gradient systems and apply it to infarct imaging. Methods The sequence The acquisition of the IR-prep image was based on the single shot 2D IR-trueFISP sequence [3]. Phase sensitive reconstruction (PSRecon) as proposed in [5] was used to make the method insensitive to TI by eliminating the need for precise nulling of normal myocardium. Phase information needed in PSRecon was obtained from a reference image acquired in the second (or later) heart beat, performed with identical gradient structures as the IR-prep image except that a low flip angle (8 in this case) was used. The low flip angle acquisition gives a reference image that is nearly proton density weighted. In both acquisitions, the linear flip angle method was used for steady state preparation before echo collection. Asymmetric echoes are used to shorten TR and hence enable the collection of more lines per shot. Fig.1 shows the sequence timing." @default.
- W2187163957 created "2016-06-24" @default.
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- W2187163957 date "2002-01-01" @default.
- W2187163957 modified "2023-09-27" @default.
- W2187163957 title "A FAST, TI INSENSITIVE INFARCT IMAGING TECHNIQUE" @default.
- W2187163957 hasPublicationYear "2002" @default.
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