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- W2187205413 abstract "SUMMARY Serafrompatientswithchronic liver disease were testedfor antibodyagainsthepatitis B surface antigen byradioimmunoassay. Theantibody was found in 25%ofpatients with alcoholic cirrhosis and in 52% when alcoholic cirrhosis was associated with portal hypertension, theseresults being significantly higher than in a matched control population. Other forms of chronicliver disease did not differ fromthecontrolpopulation. Hepatitis Bvirusinfection mightbe a factorin determining whichalcoholic patients go on to develop chronicliver diseaseandcirrhosis.The hepatitis Bvirus appears to cause widespread subclinical infection as judgedby the frequency withwhich serum surface antibody (anti-HBs) to thehepatitis Bsurface antigen (HBsAg) is found in thecommunity (Cherubin et al., 1972; Szmuness et al., 1973). The development of sensitive radioimmuno-assay and passive haemagglutination tests have markedly increased the yield of antibody positive sera (Walsh et al., 1970; Lander et al., 1971).Experience" @default.
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- W2187205413 date "1979-01-01" @default.
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- W2187205413 title "Hepatitis B,antibody inalcoholic cirrhosis" @default.
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