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- W2187355536 abstract "Objective: Two bypassing agents, activated prothrombin complex concentrates (aPCC) and recombinant factor VIIa (rFVIIa), have shown similar efficacy and safety in the treatment of bleeding episodes in patients with hemophilia and inhibitors as demonstrated through the only two head-to-head clinical trials. Given the economic burden of bypassing treatment, it is crucial to have a valid estimate of cost effectiveness of alternative treatments. The aims of this study were to conduct a systematic review of published pharmacoeconomic literature on the cost-effectiveness of aPCC versus rFVIIa to treat mild-to-moderate bleeds in patients with hemophilia and inhibitors, with a focus on the model assumptions and their impact on results." @default.
- W2187355536 created "2016-06-24" @default.
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- W2187355536 date "2011-01-01" @default.
- W2187355536 modified "2023-09-27" @default.
- W2187355536 title "Original article Systematic literature review of economics analysis on treatment of mild-to-moderate bleeds with aPCC versus rFVIIa" @default.
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