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- W2187405280 abstract "2 Abstract: This study presents a prospective analysis to investigate the pivotal role of beta2-microglobulin ( 2m) as a serum marker that may potentially help in assessment of disease activity in systemic lupus erythematosus (SLE) and chronic kidney disease (CKD) patients. This study involved a total of 70 patients; 30 patients with SLE and 40 patients with CKD compared to 42 healthy volunteers as control. Levels of 2m, anti-nuclear antibodies (ANA), anti-double strand DNA (anti-dsDNA), C-reactive protein (CRP), urea and creatinine were measured. 2m mean level of male patients was significantly (P < 0.0001 and P < 0.05) higher than females patients with SLE in stage 1 and 2 respectively. In contrast, CKD females showed a higher significant (P < 0.05) 2m level regards to males in stage 4. In SLE, ANA and 2m levels in males revealed the highest relation with SLE stages among other markers. In CKD, serum urea, CRP concentration and 2m levels in male patients exhibited higher relation with disease stages than female patients. 2m estimation may be a useful tracing marker but is correlated with gender being more related with males than females." @default.
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- W2187405280 date "2015-01-01" @default.
- W2187405280 modified "2023-09-24" @default.
- W2187405280 title "Evaluation of Beta2-Microglobulin as a Possible Biomarker for Assessment of Disease Activity in Systemic Lupus Erythematosus and Chronic Kidney Disease" @default.
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