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• W2187438462 abstract "Despite significant therapeutic advances in the treatment of multiple sclerosis (MS), the challenges facing neurologists are considerable. Because reliable predictors of sustained and progressive disability are lacking, there is a critical need for guidance regarding the definition and identification of treatment success and failure, breakthrough disease, and inadequate treatment response. Likewise, clinicians need practical treatment algorithms that focus on strategies for nonresponders, including the relative merits of drug dosage adjustment, switching therapies, and the use of combination therapies. This article identifies characteristics of patients with MS who are inadequate responders and discusses issues regarding treatment modification in these individuals. (Adv Stud Med. 2008;8(8):274-283)" @default.
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• W2187438462 date "2008-01-01" @default.
• W2187438462 modified "2023-09-27" @default.
• W2187438462 title "DEFINING SUCCESS IN MULTIPLE SCLEROSIS: TREATMENT FAILURES AND NONRESPONDERS *" @default.
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