Matches in SemOpenAlex for { <https://semopenalex.org/work/W2187520498> ?p ?o ?g. }
- W2187520498 endingPage "53; quiz 1 p following 153" @default.
- W2187520498 startingPage "143" @default.
- W2187520498 abstract "Hypersensitivity drug reactions (HDRs) vary over time in frequency, drugs involved, and clinical entities. Specific reactions are mediated by IgE, other antibody isotypes (IgG or IgM), and T cells. Nonspecific HDRs include those caused by nonsteroidal anti-inflammatory drugs (NSAIDs). beta-Lactams--the most important of which are amoxicillin and clavulanic acid--are involved in specific immunological mechanisms. Fluoroquinolones (mainly moxifloxacin, followed by ciprofloxacin and levofloxacin) can also induce HDRs mediated by IgE and T cells. In the case of radio contrast media, immediate reactions have decreased, while nonimmediate reactions, mediated by T cells, have increased. There has been a substantial rise in hypersensitivity reactions to antibiotics and latex in perioperative allergic reactions to anesthetics. NSAIDs are the most frequent drugs involved in HDRs. Five well-defined clinical entities, the most common of which is NSAID-induced urticaria/angioedema, have been proposed in a new consensus classification. Biological agents are proteins including antibodies that have been humanized in order to avoid adverse reactions. Reactions can be mediated by IgE or T cells or they may be due to an immunological imbalance. Chimeric antibodies are still in use and may have epitopes that are recognized by the immune system, resulting in allergic reactions." @default.
- W2187520498 created "2016-06-24" @default.
- W2187520498 creator A5010195936 @default.
- W2187520498 creator A5017356920 @default.
- W2187520498 creator A5043272366 @default.
- W2187520498 creator A5054299235 @default.
- W2187520498 creator A5064851701 @default.
- W2187520498 creator A5065314204 @default.
- W2187520498 creator A5079550891 @default.
- W2187520498 creator A5080009510 @default.
- W2187520498 date "2014-01-01" @default.
- W2187520498 modified "2023-10-10" @default.
- W2187520498 title "Trends in hypersensitivity drug reactions: more drugs, more response patterns, more heterogeneity." @default.
- W2187520498 cites W121884968 @default.
- W2187520498 cites W1495010403 @default.
- W2187520498 cites W1510503817 @default.
- W2187520498 cites W1521050916 @default.
- W2187520498 cites W1558532796 @default.
- W2187520498 cites W1594012740 @default.
- W2187520498 cites W1681728269 @default.
- W2187520498 cites W1717219501 @default.
- W2187520498 cites W1765914614 @default.
- W2187520498 cites W1806522924 @default.
- W2187520498 cites W1852678753 @default.
- W2187520498 cites W1964511881 @default.
- W2187520498 cites W1967022525 @default.
- W2187520498 cites W1986336710 @default.
- W2187520498 cites W1988437838 @default.
- W2187520498 cites W1994606543 @default.
- W2187520498 cites W1994855217 @default.
- W2187520498 cites W1997989273 @default.
- W2187520498 cites W1998665927 @default.
- W2187520498 cites W1999433780 @default.
- W2187520498 cites W2000593582 @default.
- W2187520498 cites W2001220984 @default.
- W2187520498 cites W2010946738 @default.
- W2187520498 cites W2012325770 @default.
- W2187520498 cites W2013487430 @default.
- W2187520498 cites W2014014324 @default.
- W2187520498 cites W2014099862 @default.
- W2187520498 cites W2017200913 @default.
- W2187520498 cites W2019949715 @default.
- W2187520498 cites W2020734514 @default.
- W2187520498 cites W2021981115 @default.
- W2187520498 cites W2024379204 @default.
- W2187520498 cites W2029386964 @default.
- W2187520498 cites W2029765423 @default.
- W2187520498 cites W2031620745 @default.
- W2187520498 cites W2032286238 @default.
- W2187520498 cites W2035669309 @default.
- W2187520498 cites W2036057434 @default.
- W2187520498 cites W2040310476 @default.
- W2187520498 cites W2041161803 @default.
- W2187520498 cites W2043992465 @default.
- W2187520498 cites W2045419076 @default.
- W2187520498 cites W2048375190 @default.
- W2187520498 cites W2048392858 @default.
- W2187520498 cites W2050347052 @default.
- W2187520498 cites W2051808004 @default.
- W2187520498 cites W2052718603 @default.
- W2187520498 cites W2053561511 @default.
- W2187520498 cites W2054488432 @default.
- W2187520498 cites W2054915531 @default.
- W2187520498 cites W2066557241 @default.
- W2187520498 cites W2071012425 @default.
- W2187520498 cites W2074964237 @default.
- W2187520498 cites W2075425574 @default.
- W2187520498 cites W2075615959 @default.
- W2187520498 cites W2076867275 @default.
- W2187520498 cites W2079898349 @default.
- W2187520498 cites W2080215759 @default.
- W2187520498 cites W2082447284 @default.
- W2187520498 cites W2083536638 @default.
- W2187520498 cites W2083670340 @default.
- W2187520498 cites W2083794637 @default.
- W2187520498 cites W2083912901 @default.
- W2187520498 cites W2087652229 @default.
- W2187520498 cites W2090402527 @default.
- W2187520498 cites W2090661205 @default.
- W2187520498 cites W2092960518 @default.
- W2187520498 cites W2094887277 @default.
- W2187520498 cites W2095225600 @default.
- W2187520498 cites W2097901958 @default.
- W2187520498 cites W2097998028 @default.
- W2187520498 cites W2100435359 @default.
- W2187520498 cites W2101524845 @default.
- W2187520498 cites W2104566233 @default.
- W2187520498 cites W2107600518 @default.
- W2187520498 cites W2107730798 @default.
- W2187520498 cites W2107800046 @default.
- W2187520498 cites W2108891904 @default.
- W2187520498 cites W2116869190 @default.
- W2187520498 cites W2124640030 @default.
- W2187520498 cites W2127412099 @default.
- W2187520498 cites W2128188573 @default.
- W2187520498 cites W2129217464 @default.
- W2187520498 cites W2129592053 @default.
- W2187520498 cites W2131093315 @default.