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- W2187538148 abstract "Tumor-to-tumor metastasis is an uncommon event and meningioma has been found as the most common intracranial tumor hosting metastasis, with the majority arising from breast cancer. In the current report we present an interesting case of a meningioma containing metastatic breast carcinoma. We also discuss the radiologic and morphologic features and the pathologic mechanisms of this phenomenon.A 60-year-old woman with history of previous breast cancerdeveloped headache, confusion and aphasia. Magnetic resonance imaging showed a left frontal extraaxial mass, focally hyperintense on T2-weighted images and heterogeneously enhancing.A left frontal craniotomy was performed and the tumor completely removed. Pathological and immumohistochemical examination revealed metastatic breast carcinoma within meningothelial meningioma with E-cadherin expression in both tumors.There are not specific radiologic features of metastasis inside meningiomas but some findings might be suggestive and, although it is a remote possibility, should always be cogitated. Our findings suggest that the role of E-cadherin seems to be significant in promoting intertumoral cellular adhesion." @default.
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- W2187538148 date "2015-01-01" @default.
- W2187538148 modified "2023-09-27" @default.
- W2187538148 title "Tumor-To-Tumor Metastasis: Intracranial Meningioma Harboring Metastatic Breast" @default.
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