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- W2187619326 abstract "Introduction: Pain management during wound dressing changes improves quality of life, patient compliance and can ease anxiety. A pain relieving gel with aloe extract to reduce inflammation, marine collagen as a humectant and 2% lidocaine-HCl provides pain relief and an environment conducive to stimulating healing. The pain relieving gel was used as an adjuvant to standard wound treatment protocols which consisted of wound dressings (foams, debriders, collagen, alginates, silver dressings, packing, etc.) selected for individual wounds. Methods: Forty seven subjects (ages 20 to 91) with painful venous ulcers, infected, pressure, diabetic foot, surgical or trauma wounds were evaluated weekly in a clinic or hospital setting. Selection criteria eliminated patients with contraindication to lidocaine or hydrogel ingredients. Subjects received an advanced wound dressing selected by the physician for wound treatment. Wounds were treated with the wound dressing. Patients responded to a numeric pain score 0-10 (least to worst) during dressing changes and these were recorded. Patients were crossed over to receive the pain relieving hydrogel under the wound dressing during subsequent dressing changes. Patient pain scores were assessed and recorded. Wound bed healing, inflammation, and diameter were assessed during dressing changes. Results: Pain scores varied from no improvement to 8 levels of pain relief with the use of the pain relieving hydrogel during dressing changes. Ninety percent of patients assessed the hydrogel as relieving pain experienced during dressing change. The mean pain relief scores using Regenecare hydrogel showed 4.5 levels of pain reduction as compared to no hydrogel use. Statistical evaluation of pain score differences with use of Regenecare vs. control analyzed by the Sign Test (Chi Square = 21.511) and by the Wilcoxin Matched Pairs Signed Ranks Test both showed p<.00001 in significance." @default.
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- W2187619326 date "2008-01-01" @default.
- W2187619326 modified "2023-09-27" @default.
- W2187619326 title "A Cross Over Clinical Study of Forty Seven Patients with Painful Deep Wounds Showed Use of a Hydrogel Containing 2% Lidocaine-HCl and Collagen as Contact Layer was Significant in Alleviating Dressing Related Pain." @default.
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