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- W2187639089 abstract "The clinical research suggests that the homeostasis of trace elements can be disrupted by diabetes mellitus.Conversely, research also suggests that early imbalances of specific elements may play an important role in upsettingnormal glucose and insulin metabolism. This study evaluated the levels of Cu, Zn, Mg & Iron and its influence on proteinoxidation which reflects the extent of oxidative stress and the thiols, which protects the proteins from oxidation in plasmaof diabetic (n=60) and diabetic retinopathy (n=40) patients. 30 healthy non-diabetic subjects were studied for comparativeanalysis. There was a significant increase in the copper (p < 0.001) and AOPP (p < 0.01), & iron (p<0.05), and decrease inZinc (p<0.001), Mg (p < 0.001) and total thiols (p<0.001) in diabetic patients without complications when compared withnormal controls. Further, an increase in copper (p < 0.001), iron (p<0.001) and AOPP (p<= 0.005) and decrease in Mg (p<0.001), Zinc (p< 0.001), total thiols (p< 0.001) in diabetic retinopathy patients when compared to the controls. Asignificant decrease in Total thiols, Zn and Mg and an increase in Iron levels was observed in DR patients whencompared with DM.Key words: Diabetes mellitus, Diabetic Retinopahy, Mg, Trace elements." @default.
- W2187639089 created "2016-06-24" @default.
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- W2187639089 date "2013-01-01" @default.
- W2187639089 modified "2023-09-27" @default.
- W2187639089 title "Influence of modified levels of plasma Magnesium, Cu, Zn and Iron levels on Thiols and protein status in diabetes mellitus and diabetic retinopathy" @default.
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