Matches in SemOpenAlex for { <https://semopenalex.org/work/W2187707041> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2187707041 abstract "pairs) pur*pyr segments can adopt intramolecular triplexes and that increasing the length of the puropyr tract reduces the dependence on low pH for structure formation, such that (GA)37 adopts an intramolecular triplex under moderate levels of negative superhelical stress (-a = 0.049) at neutral pH. This demonstrates that long purspyr segments, which are abundant in eukaryotic genomes, have the potential to adopt triplexes in vivo. Two-dimensional gel electrophoresis of the plasmids combined with chemical probing indicates that for longer sequences, multiple conformers of the intramolecular triplex exist at low pH. These conformers result from nucleation at various positions on the polypurine stretch, giving rise to different extents of relaxation at the same linking number. In addition, the metal ions co2+, Mn2+, and Mg2+ have profound effects on the pattern of chemical reactivity displayed by long purepyr segments at both neutral and low pH, indicating that quite different structures may form in the presence of divalent metal ions. Thus, the types and extent of unusual structures adopted by long pur*pyr segments are complex and heterogeneous, and are dependent on pH, supercoiling, and the presence of divalent cations." @default.
- W2187707041 created "2016-06-24" @default.
- W2187707041 creator A5008683089 @default.
- W2187707041 creator A5040500435 @default.
- W2187707041 date "1990-01-01" @default.
- W2187707041 modified "2023-10-14" @default.
- W2187707041 title "Effect of Length, Supercoiling, and pH on Intramolecular Triplex Formation" @default.
- W2187707041 cites W2036277582 @default.
- W2187707041 hasPublicationYear "1990" @default.
- W2187707041 type Work @default.
- W2187707041 sameAs 2187707041 @default.
- W2187707041 citedByCount "0" @default.
- W2187707041 crossrefType "journal-article" @default.
- W2187707041 hasAuthorship W2187707041A5008683089 @default.
- W2187707041 hasAuthorship W2187707041A5040500435 @default.
- W2187707041 hasConcept C12554922 @default.
- W2187707041 hasConcept C158456008 @default.
- W2187707041 hasConcept C169760540 @default.
- W2187707041 hasConcept C178790620 @default.
- W2187707041 hasConcept C185592680 @default.
- W2187707041 hasConcept C18705241 @default.
- W2187707041 hasConcept C2776029896 @default.
- W2187707041 hasConcept C32909587 @default.
- W2187707041 hasConcept C544153396 @default.
- W2187707041 hasConcept C552990157 @default.
- W2187707041 hasConcept C55493867 @default.
- W2187707041 hasConcept C71240020 @default.
- W2187707041 hasConcept C73573662 @default.
- W2187707041 hasConcept C74884574 @default.
- W2187707041 hasConcept C75079739 @default.
- W2187707041 hasConcept C8010536 @default.
- W2187707041 hasConcept C86803240 @default.
- W2187707041 hasConceptScore W2187707041C12554922 @default.
- W2187707041 hasConceptScore W2187707041C158456008 @default.
- W2187707041 hasConceptScore W2187707041C169760540 @default.
- W2187707041 hasConceptScore W2187707041C178790620 @default.
- W2187707041 hasConceptScore W2187707041C185592680 @default.
- W2187707041 hasConceptScore W2187707041C18705241 @default.
- W2187707041 hasConceptScore W2187707041C2776029896 @default.
- W2187707041 hasConceptScore W2187707041C32909587 @default.
- W2187707041 hasConceptScore W2187707041C544153396 @default.
- W2187707041 hasConceptScore W2187707041C552990157 @default.
- W2187707041 hasConceptScore W2187707041C55493867 @default.
- W2187707041 hasConceptScore W2187707041C71240020 @default.
- W2187707041 hasConceptScore W2187707041C73573662 @default.
- W2187707041 hasConceptScore W2187707041C74884574 @default.
- W2187707041 hasConceptScore W2187707041C75079739 @default.
- W2187707041 hasConceptScore W2187707041C8010536 @default.
- W2187707041 hasConceptScore W2187707041C86803240 @default.
- W2187707041 hasLocation W21877070411 @default.
- W2187707041 hasOpenAccess W2187707041 @default.
- W2187707041 hasPrimaryLocation W21877070411 @default.
- W2187707041 hasRelatedWork W1489143471 @default.
- W2187707041 hasRelatedWork W1502611956 @default.
- W2187707041 hasRelatedWork W1515335513 @default.
- W2187707041 hasRelatedWork W1517413858 @default.
- W2187707041 hasRelatedWork W1589149823 @default.
- W2187707041 hasRelatedWork W1972826864 @default.
- W2187707041 hasRelatedWork W1979704125 @default.
- W2187707041 hasRelatedWork W1982664123 @default.
- W2187707041 hasRelatedWork W1985199065 @default.
- W2187707041 hasRelatedWork W2019543510 @default.
- W2187707041 hasRelatedWork W2026951046 @default.
- W2187707041 hasRelatedWork W2027759281 @default.
- W2187707041 hasRelatedWork W2044884711 @default.
- W2187707041 hasRelatedWork W2078310650 @default.
- W2187707041 hasRelatedWork W2088076921 @default.
- W2187707041 hasRelatedWork W2091951389 @default.
- W2187707041 hasRelatedWork W2415002063 @default.
- W2187707041 hasRelatedWork W2489091245 @default.
- W2187707041 hasRelatedWork W2780103915 @default.
- W2187707041 hasRelatedWork W3000408942 @default.
- W2187707041 isParatext "false" @default.
- W2187707041 isRetracted "false" @default.
- W2187707041 magId "2187707041" @default.
- W2187707041 workType "article" @default.