FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2187744035> ?p ?o ?g. }

• W2187744035 endingPage "2865" @default.
• W2187744035 startingPage "2855" @default.
• W2187744035 abstract "In addition to their role in the specification of the epidermal pattern in each segment, several segment polarity genes, including gooseberry (gsb), specify cell fate in the Drosophila central nervous system (CNS). Analyses of the gsb CNS phenotype have been complicated by the fact that the previously available gsb mutants, all caused by cytologically visible deficiencies, have severe segmentation defects and also lack a number of additional genes. We have characterized two novel gsb mutants which, due to their hypomorphic nature, have CNS defects, but have only weak or no segmentation defects. These gsb alleles, as well as gsb rescue experiments, have allowed us to determine which aspects of the deficiency mutant phenotypes can be attributed to loss of gsb. gsb mutants lack U and CQ neurons, have duplicated RP2 neurons, and display posterior commissure defects. gsb neural defects, as well as the gsb cuticle defect, are differentially sensitive to the level of functional Gsb. We have used one of the novel gsb alleles in order to understand the genetic interactions between gsb, wingless (wg), and patched (ptc) during the patterning of the ventral neuroectoderm. In contrast to epidermal patterning, where Gsb is required to maintain wg transcription, we find that Gsb antagonizes the Wg signal that confers neuroblast (NB) 4-2 fate." @default.
• W2187744035 created "2016-06-24" @default.
• W2187744035 creator A5054297449 @default.
• W2187744035 creator A5054574271 @default.
• W2187744035 creator A5055945854 @default.
• W2187744035 creator A5069724925 @default.
• W2187744035 creator A5081036974 @default.
• W2187744035 date "1997-08-01" @default.
• W2187744035 modified "2023-10-14" @default.
• W2187744035 title "Genetic separation of the neural and cuticular patterning functions of <i>gooseberry</i>" @default.
• W2187744035 cites W136915679 @default.
• W2187744035 cites W1820076796 @default.
• W2187744035 cites W1911201077 @default.
• W2187744035 cites W1943532060 @default.
• W2187744035 cites W1967978971 @default.
• W2187744035 cites W1973738379 @default.
• W2187744035 cites W1982037385 @default.
• W2187744035 cites W1985962316 @default.
• W2187744035 cites W1989448686 @default.
• W2187744035 cites W2000572318 @default.
• W2187744035 cites W2008506955 @default.
• W2187744035 cites W2017661843 @default.
• W2187744035 cites W2021210221 @default.
• W2187744035 cites W2021278943 @default.
• W2187744035 cites W2023915893 @default.
• W2187744035 cites W2029265468 @default.
• W2187744035 cites W2033513529 @default.
• W2187744035 cites W2037907551 @default.
• W2187744035 cites W2038178503 @default.
• W2187744035 cites W2046820750 @default.
• W2187744035 cites W2050740079 @default.
• W2187744035 cites W2057125354 @default.
• W2187744035 cites W2081944345 @default.
• W2187744035 cites W2084137155 @default.
• W2187744035 cites W2088251261 @default.
• W2187744035 cites W2091154399 @default.
• W2187744035 cites W2098357545 @default.
• W2187744035 cites W2106125642 @default.
• W2187744035 cites W2109555585 @default.
• W2187744035 cites W2119699304 @default.
• W2187744035 cites W2141267751 @default.
• W2187744035 cites W2145034086 @default.
• W2187744035 cites W2169478707 @default.
• W2187744035 cites W2182909222 @default.
• W2187744035 cites W2186534860 @default.
• W2187744035 cites W2219694163 @default.
• W2187744035 cites W2336183000 @default.
• W2187744035 cites W2492268883 @default.
• W2187744035 cites W325216255 @default.
• W2187744035 doi "https://doi.org/10.1242/dev.124.15.2855" @default.
• W2187744035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9247329" @default.
• W2187744035 hasPublicationYear "1997" @default.
• W2187744035 type Work @default.
• W2187744035 sameAs 2187744035 @default.
• W2187744035 citedByCount "34" @default.
• W2187744035 countsByYear W21877440352012 @default.
• W2187744035 countsByYear W21877440352013 @default.
• W2187744035 countsByYear W21877440352014 @default.
• W2187744035 countsByYear W21877440352015 @default.
• W2187744035 countsByYear W21877440352017 @default.
• W2187744035 countsByYear W21877440352021 @default.
• W2187744035 crossrefType "journal-article" @default.
• W2187744035 hasAuthorship W2187744035A5054297449 @default.
• W2187744035 hasAuthorship W2187744035A5054574271 @default.
• W2187744035 hasAuthorship W2187744035A5055945854 @default.
• W2187744035 hasAuthorship W2187744035A5069724925 @default.
• W2187744035 hasAuthorship W2187744035A5081036974 @default.
• W2187744035 hasConcept C104317684 @default.
• W2187744035 hasConcept C127716648 @default.
• W2187744035 hasConcept C135073763 @default.
• W2187744035 hasConcept C143065580 @default.
• W2187744035 hasConcept C145103041 @default.
• W2187744035 hasConcept C2780915607 @default.
• W2187744035 hasConcept C39961270 @default.
• W2187744035 hasConcept C4746552 @default.
• W2187744035 hasConcept C54355233 @default.
• W2187744035 hasConcept C86803240 @default.
• W2187744035 hasConceptScore W2187744035C104317684 @default.
• W2187744035 hasConceptScore W2187744035C127716648 @default.
• W2187744035 hasConceptScore W2187744035C135073763 @default.
• W2187744035 hasConceptScore W2187744035C143065580 @default.
• W2187744035 hasConceptScore W2187744035C145103041 @default.
• W2187744035 hasConceptScore W2187744035C2780915607 @default.
• W2187744035 hasConceptScore W2187744035C39961270 @default.
• W2187744035 hasConceptScore W2187744035C4746552 @default.
• W2187744035 hasConceptScore W2187744035C54355233 @default.
• W2187744035 hasConceptScore W2187744035C86803240 @default.
• W2187744035 hasIssue "15" @default.
• W2187744035 hasLocation W21877440351 @default.
• W2187744035 hasLocation W21877440352 @default.
• W2187744035 hasOpenAccess W2187744035 @default.
• W2187744035 hasPrimaryLocation W21877440351 @default.
• W2187744035 hasRelatedWork W1530845363 @default.
• W2187744035 hasRelatedWork W1968643238 @default.
• W2187744035 hasRelatedWork W2030205636 @default.
• W2187744035 hasRelatedWork W2034103052 @default.
• W2187744035 hasRelatedWork W2037152398 @default.
• W2187744035 hasRelatedWork W2101630525 @default.

• next