FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2187750603> ?p ?o ?g. }

• W2187750603 endingPage "369" @default.
• W2187750603 startingPage "359" @default.
• W2187750603 abstract "The effect of a diet containing triglycerides of different fatty acid composition on hepatic 7alpha-hydroxylation of cholesterol was studied. 7alpha-Hydroxylation of exogenous as well as endogenous cholesterol was significantly lower in the liver of rats fed trilinolein and triolein than in those fed tripalmitin and trierucin. The concentration of cytochrome P-450 in liver microsomes was significantly lower in the rats fed tripalmitin and trierucin than in those fed triolein and trilinolein. The inhibitory effect of triolein and trilinolein on 7alpha-hydroxylation of cholesterol and the stimulatory effect of these triglycerides on the concentration of cytochrome P-450 was not due to the small amounts of peroxides present in the unsaturated triglycerides. Thus addition of the antioxidant butylated hydroxyanisol did not change the general pattern with respect to 7alpha-hydroxylation and concentration of cytochrome P-450. However, a diet consisting of peroxidized linoleic acid further decreased 7alpha-hydroxylation of cholesterol. The difference between the effect obtained with triolein and trilinolein on the one hand and trierucin and tripalmitin on the other was observed also in experiments with lower concentrations of fat in the diet and in experiments with different lighting conditions and feeding patterns. The inverse relation between cytochrome P-450 and 7alpha-hydroxylation of cholesterol, as well as results obtained with substrates for mixed-function oxidation other than cholesterol suggest that most of the changes observed due to the different diets are specific for 7alpha-hydroxylation of cholesterol. The level of cholesterol 7alpha-hydroxylase activity was found to be better related to the degree of absorption of fat than to total amount of absorbed fat or degree of unsaturation of the fat. The results are discussed in relation to previous knowledge concerning mechanisms regulating biosynthesis of bile acid." @default.
• W2187750603 created "2016-06-24" @default.
• W2187750603 creator A5037255798 @default.
• W2187750603 creator A5072704585 @default.
• W2187750603 creator A5083688723 @default.
• W2187750603 date "1978-03-01" @default.
• W2187750603 modified "2023-09-30" @default.
• W2187750603 title "Effect of different dietary triglycerides on 7alpha-hydroxylation of cholesterol and other mixed-function oxidations." @default.
• W2187750603 cites W1561848338 @default.
• W2187750603 cites W1581448740 @default.
• W2187750603 cites W1589450898 @default.
• W2187750603 cites W1775749144 @default.
• W2187750603 cites W1811754679 @default.
• W2187750603 cites W1883440365 @default.
• W2187750603 cites W1900373396 @default.
• W2187750603 cites W1966442116 @default.
• W2187750603 cites W1973495386 @default.
• W2187750603 cites W1974222663 @default.
• W2187750603 cites W1986603183 @default.
• W2187750603 cites W1986900337 @default.
• W2187750603 cites W1996217039 @default.
• W2187750603 cites W2003801590 @default.
• W2187750603 cites W2004297372 @default.
• W2187750603 cites W2013281558 @default.
• W2187750603 cites W2016319263 @default.
• W2187750603 cites W2046450133 @default.
• W2187750603 cites W2050550042 @default.
• W2187750603 cites W2053899944 @default.
• W2187750603 cites W2063403416 @default.
• W2187750603 cites W2093123664 @default.
• W2187750603 cites W2093429133 @default.
• W2187750603 cites W2118313918 @default.
• W2187750603 cites W2125547328 @default.
• W2187750603 cites W2141756157 @default.
• W2187750603 cites W2149096340 @default.
• W2187750603 cites W2171004516 @default.
• W2187750603 cites W2183664104 @default.
• W2187750603 cites W2310361929 @default.
• W2187750603 cites W2319447058 @default.
• W2187750603 cites W2412650988 @default.
• W2187750603 cites W4252620944 @default.
• W2187750603 cites W4300872921 @default.
• W2187750603 cites W46917415 @default.
• W2187750603 cites W967021459 @default.
• W2187750603 doi "https://doi.org/10.1016/s0022-2275(20)41309-4" @default.
• W2187750603 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/650092" @default.
• W2187750603 hasPublicationYear "1978" @default.
• W2187750603 type Work @default.
• W2187750603 sameAs 2187750603 @default.
• W2187750603 citedByCount "22" @default.
• W2187750603 countsByYear W21877506032018 @default.
• W2187750603 crossrefType "journal-article" @default.
• W2187750603 hasAuthorship W2187750603A5037255798 @default.
• W2187750603 hasAuthorship W2187750603A5072704585 @default.
• W2187750603 hasAuthorship W2187750603A5083688723 @default.
• W2187750603 hasBestOaLocation W21877506031 @default.
• W2187750603 hasConcept C14036430 @default.
• W2187750603 hasConcept C181199279 @default.
• W2187750603 hasConcept C185592680 @default.
• W2187750603 hasConcept C2778163477 @default.
• W2187750603 hasConcept C2781109383 @default.
• W2187750603 hasConcept C2909484148 @default.
• W2187750603 hasConcept C3019550498 @default.
• W2187750603 hasConcept C31903555 @default.
• W2187750603 hasConcept C55493867 @default.
• W2187750603 hasConcept C78458016 @default.
• W2187750603 hasConcept C86803240 @default.
• W2187750603 hasConceptScore W2187750603C14036430 @default.
• W2187750603 hasConceptScore W2187750603C181199279 @default.
• W2187750603 hasConceptScore W2187750603C185592680 @default.
• W2187750603 hasConceptScore W2187750603C2778163477 @default.
• W2187750603 hasConceptScore W2187750603C2781109383 @default.
• W2187750603 hasConceptScore W2187750603C2909484148 @default.
• W2187750603 hasConceptScore W2187750603C3019550498 @default.
• W2187750603 hasConceptScore W2187750603C31903555 @default.
• W2187750603 hasConceptScore W2187750603C55493867 @default.
• W2187750603 hasConceptScore W2187750603C78458016 @default.
• W2187750603 hasConceptScore W2187750603C86803240 @default.
• W2187750603 hasIssue "3" @default.
• W2187750603 hasLocation W21877506031 @default.
• W2187750603 hasOpenAccess W2187750603 @default.
• W2187750603 hasPrimaryLocation W21877506031 @default.
• W2187750603 hasRelatedWork W1548582471 @default.
• W2187750603 hasRelatedWork W2050484438 @default.
• W2187750603 hasRelatedWork W2126938717 @default.
• W2187750603 hasRelatedWork W2136371340 @default.
• W2187750603 hasRelatedWork W2138294190 @default.
• W2187750603 hasRelatedWork W2156113209 @default.
• W2187750603 hasRelatedWork W2187750603 @default.
• W2187750603 hasRelatedWork W2412822295 @default.
• W2187750603 hasRelatedWork W2434545434 @default.
• W2187750603 hasRelatedWork W2184071970 @default.
• W2187750603 hasVolume "19" @default.
• W2187750603 isParatext "false" @default.
• W2187750603 isRetracted "false" @default.
• W2187750603 magId "2187750603" @default.
• W2187750603 workType "article" @default.