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- W2187822295 abstract "Thelaryngeal chemoreflex (LCR)develops in infants asa primarysensory mechanism fordefending the airway fromtheaspiration ofliquids. Previous studies have hypothesized thatprolonged apneaassociated withLCR may belife threatening andmightbea causeofsuddeninfant deathsyndrome (SIDS). Inthisstudy wequantify theoutput oftherespiratory neuralnetwork, thediaphragm EMG signal, during theLCR andeupneainearlypostnatal (3-10 days)piglets. We testthehypothesis thatdiaphragm EMG activity corresponding toreflex-related eventsinvolved in clearance (restorative) mechanisms suchascoughandswallow exhibit lowercomplexity patterns, suggesting thata synchronized homogeneous groupofneuronsinthecentral respiratory network areactive during these events. Nonlinear dynamicanalysis was performed usingtheapproximate entropy(ApEn)to assesthecomplexity ofrespiratory patterns. DiaphragmEMG (EMGdia), genioglossal activity EMG (EMGgg), aswellasother physiological signals (tracheal pressure, bloodpressure and respiratory volume)were recorded from5unanesthetized chronically instrumented and intact piglets. ApEnvalues oftheEMG during coughand swallowwere foundsignificantly (p<0.05 and p<0.01 respectively) lowerthanthose ofeupneic EMG." @default.
- W2187822295 created "2016-06-24" @default.
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- W2187822295 date "2008-01-01" @default.
- W2187822295 modified "2023-09-27" @default.
- W2187822295 title "Investigating theComplexity ofRespiratory Patterns during theLaryngeal Chemoreflex" @default.
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