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• W2187834332 abstract "Loxostylis alata belongs to the family Anacardiaceae. In South Africa, the bark and leaves of Loxostylis alata are used in traditional medicine during childbirth and also to stimulate the immune system. This study was aimed at investigating the antiinflammatory and analgesic activities of the crude acetone extract of Loxostylis alata. In vivo experimental models that include egg albumin, prostaglandin E2, and histamine-induced-paw oedema, and vascular permeability test were used to screen the extract for antiinflammatory effect. While formalin-induced nociception, acetic acidinduced writhing and hot plate tests were carried out to evaluate analgesic effects of the extract. The extract inhibited egg-albumin, prostaglandin and histamine-induced oedema in a dose-dependent (50-200 mg/kg) manner. It also inhibited vascular permeability cause by acetic acid in a similar fashion. Furthermore, the extract inhibited pain induced by formalin; acetic acid and heat dosedependently (50-200 mg/kg). These findings propose the antiinflammatory and analgesic effects of" @default.
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• W2187834332 date "2014-01-01" @default.
• W2187834332 modified "2023-09-24" @default.
• W2187834332 title "ANTIINFLAMMATORY AND ANTINOCICEPTIVE ACTIVITIES OF Loxostylis alata A.SPRENG. EX RCHB (ANACARDIACEAE)" @default.
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