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- W2187836670 abstract "Summary Curculigo orchioides (Hypoxidaceae), crude hydroalcohalic rhizome extract (HAECO) and their alkaloidal and nonalkaloidal fractions (AHAFCO, NAHAFCO) were evaluated for antinociceptive activity by modified hot plate method at different dose level 100, 300 and 500mg/kg in albino wistar rats. Oral administration of 100, 300 and 500 mg/kg of rhizome extracts and fractions of C. orchioides were used for the above study and acetylsalicylic acid (100 mg/kg) was used as reference drug. Hydroalcohalic extract was fractioned into alkaloidal and non alkaloidal extracts. The result showed dose dependent action of all extracts and fractions, among these alkaloidal fractions were showed more potent antinociceptive effect than other extracts and fractions. The results of the various phytochemical tests indicated the plant to be rich in various biologically active compounds which could serve as potential source of crude drugs. Therefore, the hydroalcoholic extract and their fractions from C. orchioides have potential application as an antinociceptive for the prevention and treatment of pain, and the present findings support its traditional local uses." @default.
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- W2187836670 date "2010-01-01" @default.
- W2187836670 modified "2023-09-27" @default.
- W2187836670 title "IN-VIVO ANTINOCICEPTIVE ACTIVITY OF DIFFERENT FRACTIONS OF CURCULIGO ORCHIOIDES GAERTN. RHIZOME" @default.
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