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- W2187979246 abstract "There were a lot of studies related to global gene expression in cells infected with in- fluenza A virus. However, few studies have focused on the systematic analysis of the regulation of cell signaling cascade by influenza A virus. To understand fully the regulation of cell signaling cascade associated with influenza virus infection, we used cDNA microarray to investigate the gene expression of A549 infected with influenza A virus A/PR/8/34. Then we used the KEGG pathway database to analyze the up-regulated genes. From the results, we can see that different pathways in- cluding Antigen processing and presentation, Toll-like receptor signaling pathway, Apoptosis, Jak- STAT signaling pathway, MAPK signaling pathway and Complement and coagulation cascades were effected by the infection of influenza A virus. Our results will provide a good platform to understand the host genes regulated by influenza virus and targets for drug design." @default.
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- W2187979246 date "2008-01-01" @default.
- W2187979246 modified "2023-09-27" @default.
- W2187979246 title "Regulation of cell signaling cascades by influenza A virus" @default.
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