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• W2187997358 abstract "This study reports the effect of Anthocleista nobilis root extract on the haematological indices of poultry chicken challenged with Newcastle disease virus (NDV). Eighteen (18)-weeks-old chickens were used for this study. They were divided into 3 groups, A (chickens infected + treatment), B (chickens infected without treatment) and C (control). Groups A and B were challenged with Newcastle disease virus (NDV). Group A and C were given ethanolic root extract of A. nobilis orally at intervals of 6 h at 0.5mg per 100g of body weight for 28 days. All the chickens were given tetracycline antibiotic to eliminate bacterial infections. The average body weight and the temperature were monitored. The cytological examination of the chickens in group B showed that there was ulceration in the intestinal lining. All values for blood parameters were within the normal range for chickens before they were challenged with NDV. From our findings most of hematological indices of poultry chickens tend towards normal after treatment with the root extract of A. nobilis. This showed the ability of this plant extract to impact immunity in chickens suffering from Newcastle disease (ND). The packed cell volume (PCV), hemoglobin (Hb) and full blood count (TWBCC) were significantly different (P 0.05) among the three groups, A (33.3% and 33.8% respectively), B (32.4%) and C (32.1%). They fell within the normal range of 30.0%-36.0%. This showed that the NDV did not affect that aspect. The study indicated a drop in the hematological indices of the infected and untreated chickens (Group B) while those of group A and C fell within normal range. The study showed that ethanolic root extract of Anthocleista nobilis was able to correct the haematological and physiological alteration associated with Newcastle disease among infected poultry chickens. The ability of group A poultry chickens to tend towards normal after treatment are physiological evidences of the antiviral effect of the root extract of A. nobilis on hematological indices of the poultry chickens studies. The study also showed that Anthocleista nobilis root extract was able to prevent further NDV infection of the poultry chickens. Thus, further studies on phyto-chemical and toxicological properties of Anthocleista nobilis as well as its antiviral property are advocated. (Ayodele PO, Okonko IO, Okerentugba PO, Nwanze JC, Onoh CC. Effect of Anthocleista nobilis root extract on the haematological indices of poultry chicken challenged with Newcastle disease virus (NDV). Nat Sci 2013;11(3):82-xx). (ISSN: 1545-0740). http://www.sciencepub.net/nature . 13" @default.
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• W2187997358 date "2013-01-01" @default.
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• W2187997358 title "Effect of Anthocleista nobilis root extract on the haematological indices of poultry chicken challenged with Newcastle disease virus (NDV)" @default.
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