Matches in SemOpenAlex for { <https://semopenalex.org/work/W2188041955> ?p ?o ?g. }
- W2188041955 endingPage "547" @default.
- W2188041955 startingPage "537" @default.
- W2188041955 abstract "ABSTRACT The mouse hematopoietic marker Sca-1, encoded by the Ly-6E.1 and Ly-6A.2 genes, has been instrumental in the enrichment and characterization of the stem cell for the adult blood system. In the studies reported here, we use Ly-6E.1 genomic fragments to direct expression of a lacZ marker transgene in vivo to study Ly-6E.1 specific regulatory elements in the hematopoietic stem cell and to localize these cells in the developing mouse embryo. We demonstrate that a region approximately 9 kb downstream from the transcriptional start site is required for the distinct, restricted expression pattern of the Ly-6E.1-lacZ transgene within adult hematopoietic stem cells and embryos. We also demonstrate that viable and functional lacZ-expressing hematopoietic stem cells can be enriched by FDG staining and flow cytometric sorting. The Ly-6E.1-lacZ-mediated enrichment of hematopoietic stem cells from adult transgenic bone marrow in combination with the temporal expression pattern of the transgene in the pro/mesonephros suggest an intraembryonic site of development for these cells in the mouse." @default.
- W2188041955 created "2016-06-24" @default.
- W2188041955 creator A5030608693 @default.
- W2188041955 creator A5036547753 @default.
- W2188041955 creator A5041903342 @default.
- W2188041955 creator A5078775033 @default.
- W2188041955 date "1997-01-15" @default.
- W2188041955 modified "2023-10-11" @default.
- W2188041955 title "Expression of the Ly-6E.1 (Sca-1) transgene in adult hematopoietic stem cells and the developing mouse embryo" @default.
- W2188041955 cites W126778996 @default.
- W2188041955 cites W1556415839 @default.
- W2188041955 cites W1559864704 @default.
- W2188041955 cites W1602164070 @default.
- W2188041955 cites W1625377704 @default.
- W2188041955 cites W1625850179 @default.
- W2188041955 cites W1705893231 @default.
- W2188041955 cites W1972736348 @default.
- W2188041955 cites W1973035870 @default.
- W2188041955 cites W1980358100 @default.
- W2188041955 cites W1994746388 @default.
- W2188041955 cites W1995716801 @default.
- W2188041955 cites W1997541508 @default.
- W2188041955 cites W2008661167 @default.
- W2188041955 cites W2014294219 @default.
- W2188041955 cites W2023010381 @default.
- W2188041955 cites W2028196271 @default.
- W2188041955 cites W2032528704 @default.
- W2188041955 cites W2058150256 @default.
- W2188041955 cites W2066771603 @default.
- W2188041955 cites W2070076558 @default.
- W2188041955 cites W2070879288 @default.
- W2188041955 cites W2074657665 @default.
- W2188041955 cites W2081262189 @default.
- W2188041955 cites W2085326817 @default.
- W2188041955 cites W2086986041 @default.
- W2188041955 cites W2093874299 @default.
- W2188041955 cites W2096998693 @default.
- W2188041955 cites W2104931922 @default.
- W2188041955 cites W2105695958 @default.
- W2188041955 cites W2117004479 @default.
- W2188041955 cites W2118299921 @default.
- W2188041955 cites W2136287764 @default.
- W2188041955 cites W2150409084 @default.
- W2188041955 cites W2156933327 @default.
- W2188041955 cites W2163168560 @default.
- W2188041955 cites W2336909995 @default.
- W2188041955 cites W2415901136 @default.
- W2188041955 cites W2885580364 @default.
- W2188041955 cites W4236523744 @default.
- W2188041955 cites W4313305922 @default.
- W2188041955 doi "https://doi.org/10.1242/dev.124.2.537" @default.
- W2188041955 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9053329" @default.
- W2188041955 hasPublicationYear "1997" @default.
- W2188041955 type Work @default.
- W2188041955 sameAs 2188041955 @default.
- W2188041955 citedByCount "70" @default.
- W2188041955 countsByYear W21880419552012 @default.
- W2188041955 countsByYear W21880419552013 @default.
- W2188041955 countsByYear W21880419552014 @default.
- W2188041955 countsByYear W21880419552015 @default.
- W2188041955 countsByYear W21880419552017 @default.
- W2188041955 countsByYear W21880419552018 @default.
- W2188041955 countsByYear W21880419552020 @default.
- W2188041955 countsByYear W21880419552021 @default.
- W2188041955 crossrefType "journal-article" @default.
- W2188041955 hasAuthorship W2188041955A5030608693 @default.
- W2188041955 hasAuthorship W2188041955A5036547753 @default.
- W2188041955 hasAuthorship W2188041955A5041903342 @default.
- W2188041955 hasAuthorship W2188041955A5078775033 @default.
- W2188041955 hasConcept C102230213 @default.
- W2188041955 hasConcept C104317684 @default.
- W2188041955 hasConcept C109159458 @default.
- W2188041955 hasConcept C136302470 @default.
- W2188041955 hasConcept C141035611 @default.
- W2188041955 hasConcept C145103041 @default.
- W2188041955 hasConcept C153911025 @default.
- W2188041955 hasConcept C2022786 @default.
- W2188041955 hasConcept C20875687 @default.
- W2188041955 hasConcept C2778086970 @default.
- W2188041955 hasConcept C2778630268 @default.
- W2188041955 hasConcept C28328180 @default.
- W2188041955 hasConcept C54355233 @default.
- W2188041955 hasConcept C553184892 @default.
- W2188041955 hasConcept C86803240 @default.
- W2188041955 hasConcept C95444343 @default.
- W2188041955 hasConceptScore W2188041955C102230213 @default.
- W2188041955 hasConceptScore W2188041955C104317684 @default.
- W2188041955 hasConceptScore W2188041955C109159458 @default.
- W2188041955 hasConceptScore W2188041955C136302470 @default.
- W2188041955 hasConceptScore W2188041955C141035611 @default.
- W2188041955 hasConceptScore W2188041955C145103041 @default.
- W2188041955 hasConceptScore W2188041955C153911025 @default.
- W2188041955 hasConceptScore W2188041955C2022786 @default.
- W2188041955 hasConceptScore W2188041955C20875687 @default.
- W2188041955 hasConceptScore W2188041955C2778086970 @default.
- W2188041955 hasConceptScore W2188041955C2778630268 @default.
- W2188041955 hasConceptScore W2188041955C28328180 @default.
- W2188041955 hasConceptScore W2188041955C54355233 @default.