Matches in SemOpenAlex for { <https://semopenalex.org/work/W2188177426> ?p ?o ?g. }
- W2188177426 endingPage "5008" @default.
- W2188177426 startingPage "4999" @default.
- W2188177426 abstract "The small guanine nucleotide binding protein p21(Ras) plays an important role in the activation of the Raf kinase. However, the precise mechanism by which Raf is activated remains unclear. It has been proposed that the sole function of p21(Ras )in Raf activation is to recruit Raf to the plasma membrane. We have used Drosophila embryos to examine the mechanism of Raf (Draf) activation in the complete absence of p21(Ras) (Ras1). We demonstrate that the role of Ras1 in Draf activation is not limited to the translocation of Draf to the membrane through a Ras1-Draf association. In addition, Ras1 is essential for the activation of an additional factor which in turn activates Draf." @default.
- W2188177426 created "2016-06-24" @default.
- W2188177426 creator A5059403398 @default.
- W2188177426 creator A5071083794 @default.
- W2188177426 creator A5087921962 @default.
- W2188177426 date "1998-12-15" @default.
- W2188177426 modified "2023-09-27" @default.
- W2188177426 title "Dual function of Ras in Raf activation" @default.
- W2188177426 cites W127569585 @default.
- W2188177426 cites W1487981797 @default.
- W2188177426 cites W1562699269 @default.
- W2188177426 cites W1772563489 @default.
- W2188177426 cites W1938204331 @default.
- W2188177426 cites W1971977518 @default.
- W2188177426 cites W1972812612 @default.
- W2188177426 cites W1976410844 @default.
- W2188177426 cites W1977186059 @default.
- W2188177426 cites W1982813290 @default.
- W2188177426 cites W1986947870 @default.
- W2188177426 cites W198944900 @default.
- W2188177426 cites W1991760443 @default.
- W2188177426 cites W1993202007 @default.
- W2188177426 cites W1995603763 @default.
- W2188177426 cites W2000786512 @default.
- W2188177426 cites W2001520967 @default.
- W2188177426 cites W2007155214 @default.
- W2188177426 cites W2011184275 @default.
- W2188177426 cites W2014908429 @default.
- W2188177426 cites W2016445852 @default.
- W2188177426 cites W2018372349 @default.
- W2188177426 cites W2019661351 @default.
- W2188177426 cites W2019687915 @default.
- W2188177426 cites W2027583953 @default.
- W2188177426 cites W2028170357 @default.
- W2188177426 cites W2030992928 @default.
- W2188177426 cites W2031066086 @default.
- W2188177426 cites W2041776106 @default.
- W2188177426 cites W2043775652 @default.
- W2188177426 cites W2048983596 @default.
- W2188177426 cites W2056257769 @default.
- W2188177426 cites W2056750804 @default.
- W2188177426 cites W2060840912 @default.
- W2188177426 cites W2060981498 @default.
- W2188177426 cites W2061038088 @default.
- W2188177426 cites W2062427243 @default.
- W2188177426 cites W2064729120 @default.
- W2188177426 cites W2064801441 @default.
- W2188177426 cites W2066696278 @default.
- W2188177426 cites W2067524077 @default.
- W2188177426 cites W2070023258 @default.
- W2188177426 cites W2071993841 @default.
- W2188177426 cites W2077086907 @default.
- W2188177426 cites W2080920431 @default.
- W2188177426 cites W2086419819 @default.
- W2188177426 cites W2095365445 @default.
- W2188177426 cites W2114516322 @default.
- W2188177426 cites W2117669008 @default.
- W2188177426 cites W2130847193 @default.
- W2188177426 cites W2132946260 @default.
- W2188177426 cites W2155615473 @default.
- W2188177426 cites W2160310997 @default.
- W2188177426 cites W2164090732 @default.
- W2188177426 cites W2167096602 @default.
- W2188177426 cites W2341080136 @default.
- W2188177426 cites W4230279981 @default.
- W2188177426 doi "https://doi.org/10.1242/dev.125.24.4999" @default.
- W2188177426 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9811584" @default.
- W2188177426 hasPublicationYear "1998" @default.
- W2188177426 type Work @default.
- W2188177426 sameAs 2188177426 @default.
- W2188177426 citedByCount "22" @default.
- W2188177426 countsByYear W21881774262014 @default.
- W2188177426 countsByYear W21881774262018 @default.
- W2188177426 crossrefType "journal-article" @default.
- W2188177426 hasAuthorship W2188177426A5059403398 @default.
- W2188177426 hasAuthorship W2188177426A5071083794 @default.
- W2188177426 hasAuthorship W2188177426A5087921962 @default.
- W2188177426 hasConcept C104317684 @default.
- W2188177426 hasConcept C126619667 @default.
- W2188177426 hasConcept C138626823 @default.
- W2188177426 hasConcept C14036430 @default.
- W2188177426 hasConcept C184235292 @default.
- W2188177426 hasConcept C55493867 @default.
- W2188177426 hasConcept C62478195 @default.
- W2188177426 hasConcept C86803240 @default.
- W2188177426 hasConcept C95444343 @default.
- W2188177426 hasConceptScore W2188177426C104317684 @default.
- W2188177426 hasConceptScore W2188177426C126619667 @default.
- W2188177426 hasConceptScore W2188177426C138626823 @default.
- W2188177426 hasConceptScore W2188177426C14036430 @default.
- W2188177426 hasConceptScore W2188177426C184235292 @default.
- W2188177426 hasConceptScore W2188177426C55493867 @default.
- W2188177426 hasConceptScore W2188177426C62478195 @default.
- W2188177426 hasConceptScore W2188177426C86803240 @default.
- W2188177426 hasConceptScore W2188177426C95444343 @default.
- W2188177426 hasIssue "24" @default.
- W2188177426 hasLocation W21881774261 @default.
- W2188177426 hasLocation W21881774262 @default.