Matches in SemOpenAlex for { <https://semopenalex.org/work/W2188217811> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2188217811 abstract "Objective: To study the analgesic effect of Caryophyllus aromaticus (flower buds) by formalin test in albino rats. Albino rats of either sex were taken and divided into 7 groups with 6 animals in each for central and peripheral analgesic activity by formalin test. 5% formalin is injected into the right dorsal surface of a hind paw of rat after half an hour of drug administration and the time the animal spent licking the paw was recorded as early phase (0-5 min after injection) and late phase (15-30 min after injection). Caryophyllus aromaticus was used in a dose of 150,300 and 600mg/kg i.p. The drug used for central analgesic activity was Pethidine (5mg/kg, i.p) and Naloxone (1mg/kg) with 300mg/kg of Caryophyllus aromaticus i.p to study the central analgesic activity. The drug used for peripheral analgesic activity was Ketorolac (10mg/kg, i.p). A control group was maintained in all models. Results revealed that in Caryophyllus aromaticus300mg/kg significantly decreased the reaction time of early phase in formalin test similar to Pethidine whereas the combination of Naloxone and Caryophyllus aromaticus 300mg/kg increased the reaction time of early phase, indicating that Naloxone inhibits the analgesic effect of Caryophyllus aromaticus. Caryophyllus aromaticus 300mg/kg significantly decreased the reaction time of late phase also. In Conclusion: Caryophyllus aromaticus (flower buds) possesses significant central and peripheral analgesic activity and acts through opioid receptors." @default.
- W2188217811 created "2016-06-24" @default.
- W2188217811 creator A5022506996 @default.
- W2188217811 creator A5068074042 @default.
- W2188217811 creator A5068164194 @default.
- W2188217811 date "2014-01-01" @default.
- W2188217811 modified "2023-09-26" @default.
- W2188217811 title "Analgesic Effect of Caryophyllus aromaticus by Formalin Test in Albino Rats" @default.
- W2188217811 cites W1999189267 @default.
- W2188217811 hasPublicationYear "2014" @default.
- W2188217811 type Work @default.
- W2188217811 sameAs 2188217811 @default.
- W2188217811 citedByCount "0" @default.
- W2188217811 crossrefType "journal-article" @default.
- W2188217811 hasAuthorship W2188217811A5022506996 @default.
- W2188217811 hasAuthorship W2188217811A5068074042 @default.
- W2188217811 hasAuthorship W2188217811A5068164194 @default.
- W2188217811 hasConcept C170493617 @default.
- W2188217811 hasConcept C185592680 @default.
- W2188217811 hasConcept C2778750930 @default.
- W2188217811 hasConcept C2780723003 @default.
- W2188217811 hasConcept C2780820201 @default.
- W2188217811 hasConcept C2781063702 @default.
- W2188217811 hasConcept C2781168792 @default.
- W2188217811 hasConcept C55493867 @default.
- W2188217811 hasConcept C71924100 @default.
- W2188217811 hasConcept C98274493 @default.
- W2188217811 hasConceptScore W2188217811C170493617 @default.
- W2188217811 hasConceptScore W2188217811C185592680 @default.
- W2188217811 hasConceptScore W2188217811C2778750930 @default.
- W2188217811 hasConceptScore W2188217811C2780723003 @default.
- W2188217811 hasConceptScore W2188217811C2780820201 @default.
- W2188217811 hasConceptScore W2188217811C2781063702 @default.
- W2188217811 hasConceptScore W2188217811C2781168792 @default.
- W2188217811 hasConceptScore W2188217811C55493867 @default.
- W2188217811 hasConceptScore W2188217811C71924100 @default.
- W2188217811 hasConceptScore W2188217811C98274493 @default.
- W2188217811 hasLocation W21882178111 @default.
- W2188217811 hasOpenAccess W2188217811 @default.
- W2188217811 hasPrimaryLocation W21882178111 @default.
- W2188217811 hasRelatedWork W2001444209 @default.
- W2188217811 hasRelatedWork W2100515304 @default.
- W2188217811 hasRelatedWork W217699675 @default.
- W2188217811 hasRelatedWork W2181634185 @default.
- W2188217811 hasRelatedWork W2184899139 @default.
- W2188217811 hasRelatedWork W2186790338 @default.
- W2188217811 hasRelatedWork W2268973769 @default.
- W2188217811 hasRelatedWork W2292383171 @default.
- W2188217811 hasRelatedWork W2317974406 @default.
- W2188217811 hasRelatedWork W2320858572 @default.
- W2188217811 hasRelatedWork W2783334822 @default.
- W2188217811 hasRelatedWork W2911255501 @default.
- W2188217811 hasRelatedWork W3154474240 @default.
- W2188217811 hasRelatedWork W3186212587 @default.
- W2188217811 hasRelatedWork W58830474 @default.
- W2188217811 hasRelatedWork W1768493948 @default.
- W2188217811 hasRelatedWork W2052587717 @default.
- W2188217811 hasRelatedWork W2181473260 @default.
- W2188217811 hasRelatedWork W2182029287 @default.
- W2188217811 hasRelatedWork W2405687358 @default.
- W2188217811 isParatext "false" @default.
- W2188217811 isRetracted "false" @default.
- W2188217811 magId "2188217811" @default.
- W2188217811 workType "article" @default.