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- W2188219965 abstract "Cyclandelate, a vasoactive substance consisting of the mandelic acid ester of 3,3,5-trimethylcyclohexanol, was administered to 10 patients with cerebrovascular and/or peripheral vascular disease. Blood specimens were collected at 1 − 6 h after oral administration of 1600 mg cyclandelate, and the ester and acid were extracted from plasma in acid medium using n-hexane/isopropyl alcohol. The concentrations were determined by a high-performance liquid chromatography isocratic system. The highest plasma cyclandelate concentrations were detected at the third hour, whereas plasma mandelic acid concentrations were still increasing 6 h after administration." @default.
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- W2188219965 date "1990-07-01" @default.
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- W2188219965 title "Determination of Plasma Concentrations of Cyclandelate and Mandelic Acid in Patients with Generalized Atherosclerotic Vasculopathy Treated with Oral Cyclandelate" @default.
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- W2188219965 doi "https://doi.org/10.1177/030006059001800402" @default.
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