FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2188294568> ?p ?o ?g. }

• W2188294568 endingPage "159" @default.
• W2188294568 startingPage "152" @default.
• W2188294568 abstract "Adult male mice exposed to long-term intermittent hypoxia (LTIH), modeling sleep apnea oxygenation patterns, develop nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-dependent residual hypersomnolence and oxidative injury in select brain regions, including wake-active regions. Premenopausal females are less susceptible to selective oxidative brain injuries. We sought to determine whether female mice exposed to LTIH would confer resistance to LTIH-induced wake impairments and oxidative injuries.Young adult male and female C57BI/6J mice were studied in a university laboratory.Mice were randomly assigned to either LTIH or sham LTIH for 8 weeks. Total (24-h) wake time and mean sleep latency were measured under 2 conditions: rested and following 6 hours of enforced wakefulness. NADPH oxidase activation, carbonylation, and lipid peroxidation assays were also performed to assess sex differences in oxidative responses to LTIH.In contrast with the significant LTIH-induced wake impairments observed in male mice, females following LTIH showed normal wake times and sleep latencies. Female mice revealed less baseline carbonylation and less carbonylation following LTIH but showed robust NADPH oxidase activation and lipid peroxidation. In contrast with the female relative resistance to LTIH sleepiness, female mice showed more-pronounced sleepiness and delta response after enforced wakefulness.Despite a robust oxidative response to LTIH, age-matched female mice may be protected, at least temporarily, from LTIH wake impairments by lower basal carbonylation. In contrast, females show greater wake impairments after sleep deprivation. We hypothesize sex differences in polysomnographic predictors of sleepiness and residual sleepiness in humans with sleep apnea." @default.
• W2188294568 created "2016-06-24" @default.
• W2188294568 creator A5009386513 @default.
• W2188294568 creator A5024529808 @default.
• W2188294568 creator A5051051576 @default.
• W2188294568 creator A5060072768 @default.
• W2188294568 creator A5065903254 @default.
• W2188294568 creator A5072202763 @default.
• W2188294568 creator A5089490467 @default.
• W2188294568 date "2006-02-01" @default.
• W2188294568 modified "2023-10-18" @default.
• W2188294568 title "Sex Differences in Susceptibility to Oxidative Injury and Sleepiness From Intermittent Hypoxia" @default.
• W2188294568 cites W128520200 @default.
• W2188294568 cites W1503425915 @default.
• W2188294568 cites W180575469 @default.
• W2188294568 cites W1922939517 @default.
• W2188294568 cites W1954454186 @default.
• W2188294568 cites W1963859198 @default.
• W2188294568 cites W1971701992 @default.
• W2188294568 cites W1979386519 @default.
• W2188294568 cites W1985353602 @default.
• W2188294568 cites W1988645552 @default.
• W2188294568 cites W1994227705 @default.
• W2188294568 cites W2001602698 @default.
• W2188294568 cites W2015667309 @default.
• W2188294568 cites W2027450779 @default.
• W2188294568 cites W2051849035 @default.
• W2188294568 cites W2066839027 @default.
• W2188294568 cites W2070991943 @default.
• W2188294568 cites W2083860194 @default.
• W2188294568 cites W2092035523 @default.
• W2188294568 cites W2097741198 @default.
• W2188294568 cites W2098412291 @default.
• W2188294568 cites W2103163472 @default.
• W2188294568 cites W2119063805 @default.
• W2188294568 cites W2120788437 @default.
• W2188294568 cites W2125365953 @default.
• W2188294568 cites W2129337692 @default.
• W2188294568 cites W2136431713 @default.
• W2188294568 cites W2147993424 @default.
• W2188294568 cites W2150168916 @default.
• W2188294568 cites W2153945143 @default.
• W2188294568 cites W2161936216 @default.
• W2188294568 cites W2167365741 @default.
• W2188294568 cites W2168259756 @default.
• W2188294568 cites W2182670779 @default.
• W2188294568 cites W2186088674 @default.
• W2188294568 cites W2333343699 @default.
• W2188294568 cites W2418061457 @default.
• W2188294568 cites W70841740 @default.
• W2188294568 doi "https://doi.org/10.1093/sleep/29.2.152" @default.
• W2188294568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16494082" @default.
• W2188294568 hasPublicationYear "2006" @default.
• W2188294568 type Work @default.
• W2188294568 sameAs 2188294568 @default.
• W2188294568 citedByCount "38" @default.
• W2188294568 countsByYear W21882945682012 @default.
• W2188294568 countsByYear W21882945682013 @default.
• W2188294568 countsByYear W21882945682014 @default.
• W2188294568 countsByYear W21882945682015 @default.
• W2188294568 countsByYear W21882945682017 @default.
• W2188294568 countsByYear W21882945682018 @default.
• W2188294568 countsByYear W21882945682019 @default.
• W2188294568 countsByYear W21882945682020 @default.
• W2188294568 countsByYear W21882945682021 @default.
• W2188294568 countsByYear W21882945682022 @default.
• W2188294568 countsByYear W21882945682023 @default.
• W2188294568 crossrefType "journal-article" @default.
• W2188294568 hasAuthorship W2188294568A5009386513 @default.
• W2188294568 hasAuthorship W2188294568A5024529808 @default.
• W2188294568 hasAuthorship W2188294568A5051051576 @default.
• W2188294568 hasAuthorship W2188294568A5060072768 @default.
• W2188294568 hasAuthorship W2188294568A5065903254 @default.
• W2188294568 hasAuthorship W2188294568A5072202763 @default.
• W2188294568 hasAuthorship W2188294568A5089490467 @default.
• W2188294568 hasBestOaLocation W21882945681 @default.
• W2188294568 hasConcept C118552586 @default.
• W2188294568 hasConcept C121446783 @default.
• W2188294568 hasConcept C126322002 @default.
• W2188294568 hasConcept C134018914 @default.
• W2188294568 hasConcept C178790620 @default.
• W2188294568 hasConcept C181199279 @default.
• W2188294568 hasConcept C185592680 @default.
• W2188294568 hasConcept C2776006263 @default.
• W2188294568 hasConcept C2776151105 @default.
• W2188294568 hasConcept C2777935920 @default.
• W2188294568 hasConcept C2777989768 @default.
• W2188294568 hasConcept C2778329153 @default.
• W2188294568 hasConcept C2779320081 @default.
• W2188294568 hasConcept C2780796939 @default.
• W2188294568 hasConcept C2780829032 @default.
• W2188294568 hasConcept C38485361 @default.
• W2188294568 hasConcept C522805319 @default.
• W2188294568 hasConcept C540031477 @default.
• W2188294568 hasConcept C55493867 @default.
• W2188294568 hasConcept C71924100 @default.
• W2188294568 hasConcept C7836513 @default.
• W2188294568 hasConcept C86803240 @default.

• next