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- W2188295930 abstract "OF THE THESIS ELECTRICALLY ACTIVE MICROARRAY OF 3D CARBON MEMS ELECTRODES FOR PATHOGEN DETECTION SYSTEMS by Jiae Shin Master of Science in Mechanical Engineering San Diego State University, 2008 The ability to isolate and concentrate pathogens (bacteria, virus, etc), biomolecules and any sub-micron particle is critical to many biomedical applications, including diagnosis for cancer and infectious disease (SARS, deadly flu strains, STD, etc). Conventional twodimensional active microarrays have been used with success for the manipulation of biomolecules including DNA. However they have a major drawback of inability to process relatively ‘large-volume’ samples useful in oncology and infectious disease applications. This thesis presents an active microarray that exploits electrokinetic (electrophoresis and dielectrophoresis) forces for its hybridization method using 3D carbon electrodes that will enable the large volume manipulation for pathogen detection. Carbon electrodes are fabricated using C-MEMS (Carbon MEMS) technology that is emerging as a very exciting research area nowadays since carbon materials have fascinating physical, chemical, mechanical and electrical properties and it also provides the advantage of low cost. The chip fabricated using C-MEMS technology will be packaged and the efficiency of separation and accumulation of the 3D electrodes on the chip will be tested by manipulating negatively charged polycarboxylate 2 m beads in 50 mM histidine buffer." @default.
- W2188295930 created "2016-06-24" @default.
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- W2188295930 date "2008-01-01" @default.
- W2188295930 modified "2023-09-27" @default.
- W2188295930 title "ELECTRICALLY ACTIVE MICROARRAY OF 3D CARBON MEMS ELECTRODES FOR PATHOGEN DETECTION SYSTEMS" @default.
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