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• W2188459559 abstract "The expression pattern of stress (heat shock) proteins (HSPs) in cancer cells is frequently different from that observed in normal cells; most often some stress-inducible HSPs are constitutively and highly expressed. The objective of this study was to determine the prognostic significance of stress proteins HSP70i and HSP27 in non-small cell lung carcinoma (NSCLC).An immunohistochemical procedure that enables unambiguous detection of HSP70i protein was used.Strong HSP70i staining showed a survival advantage, although multivariate analysis did not confirm this result. There was an evident correlation between HSP27 overexpression and survival of patients and the results were confirmed by multivariate analysis: 70% of patients with HSP27-negative tumors died within one year after the surgery.Our data suggest that HSP27 and HSP70i positivity may represent a favorable prognostic factor in NSCLC." @default.
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• W2188459559 date "2008-04-04" @default.
• W2188459559 modified "2023-10-03" @default.
• W2188459559 title "Stress proteins HSP27 and HSP70i predict survival in non-small cell lung carcinoma." @default.
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• W2188459559 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18383892" @default.
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