FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2188613639> ?p ?o ?g. }

• W2188613639 endingPage "61" @default.
• W2188613639 startingPage "55" @default.
• W2188613639 abstract "Curcumin (diferuloylmethane) exhibited potent inhibitory activities against proliferation and induced apoptosis in several tumor cell lines. It was recently reported that curcumin induced cell cycle arrest in several human cancer cell lines. However, the exact mechanisms are unclear.Flow cytometry was used to analyze the cell cycle in human colon cancer colo 205 cells treated with various concentrations of curcumin for 48 h. In order to further understand the mechanism of curcumin-induced G2/M arrest, the checkpoint associated with enzymes of the cell cycle were also investigated by Western blotting methods.Curcumin induced G2/M arrest in the examined cells and these effects were dose- and time-dependent. Futhermore, curcumin induced Wee1 expression and decreased the Cdc25c, cyclin B1 and CDK1 expressions, resulting in the induction of G2/M cell cycle arrest in the colo 205 cells. The cDNA microarray assay was also employed to confirm gene expressions (mRNA Wee1, Cdc25c, cyclin B1 and CDK1).The results indicate that curcumin promoted the gene expression of Wee1 and inhibited that of Cdc25c, CDK1 and cyclin B1." @default.
• W2188613639 created "2016-06-24" @default.
• W2188613639 creator A5025655381 @default.
• W2188613639 creator A5050783027 @default.
• W2188613639 creator A5051830346 @default.
• W2188613639 creator A5076528078 @default.
• W2188613639 creator A5087091914 @default.
• W2188613639 date "2006-01-01" @default.
• W2188613639 modified "2023-10-18" @default.
• W2188613639 title "Down-regulation of Cdc25c, CDK1 and Cyclin B1 and Up-regulation of Wee1 by Curcumin Promotes Human Colon Cancer Colo 205 Cell Entry into G2/M-phase of Cell Cycle." @default.
• W2188613639 cites W1539145809 @default.
• W2188613639 cites W1541317652 @default.
• W2188613639 cites W1547348954 @default.
• W2188613639 cites W1559639669 @default.
• W2188613639 cites W1909321451 @default.
• W2188613639 cites W1972434237 @default.
• W2188613639 cites W1972733003 @default.
• W2188613639 cites W1981797176 @default.
• W2188613639 cites W2017975463 @default.
• W2188613639 cites W2021931700 @default.
• W2188613639 cites W2029080338 @default.
• W2188613639 cites W2035308484 @default.
• W2188613639 cites W2040429946 @default.
• W2188613639 cites W2040470926 @default.
• W2188613639 cites W2056743601 @default.
• W2188613639 cites W2070878775 @default.
• W2188613639 cites W2084147994 @default.
• W2188613639 cites W2099023764 @default.
• W2188613639 cites W2128635872 @default.
• W2188613639 cites W2130066394 @default.
• W2188613639 cites W2132737274 @default.
• W2188613639 cites W2145045978 @default.
• W2188613639 cites W2407170803 @default.
• W2188613639 cites W4952422 @default.
• W2188613639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31394642" @default.
• W2188613639 hasPublicationYear "2006" @default.
• W2188613639 type Work @default.
• W2188613639 sameAs 2188613639 @default.
• W2188613639 citedByCount "1" @default.
• W2188613639 countsByYear W21886136392020 @default.
• W2188613639 crossrefType "journal-article" @default.
• W2188613639 hasAuthorship W2188613639A5025655381 @default.
• W2188613639 hasAuthorship W2188613639A5050783027 @default.
• W2188613639 hasAuthorship W2188613639A5051830346 @default.
• W2188613639 hasAuthorship W2188613639A5076528078 @default.
• W2188613639 hasAuthorship W2188613639A5087091914 @default.
• W2188613639 hasConcept C105696609 @default.
• W2188613639 hasConcept C120089663 @default.
• W2188613639 hasConcept C120504264 @default.
• W2188613639 hasConcept C153911025 @default.
• W2188613639 hasConcept C16438837 @default.
• W2188613639 hasConcept C185592680 @default.
• W2188613639 hasConcept C190283241 @default.
• W2188613639 hasConcept C199835354 @default.
• W2188613639 hasConcept C2778250585 @default.
• W2188613639 hasConcept C2778437423 @default.
• W2188613639 hasConcept C2781252693 @default.
• W2188613639 hasConcept C29537977 @default.
• W2188613639 hasConcept C50001416 @default.
• W2188613639 hasConcept C502942594 @default.
• W2188613639 hasConcept C55493867 @default.
• W2188613639 hasConcept C62112901 @default.
• W2188613639 hasConcept C86803240 @default.
• W2188613639 hasConcept C9743823 @default.
• W2188613639 hasConceptScore W2188613639C105696609 @default.
• W2188613639 hasConceptScore W2188613639C120089663 @default.
• W2188613639 hasConceptScore W2188613639C120504264 @default.
• W2188613639 hasConceptScore W2188613639C153911025 @default.
• W2188613639 hasConceptScore W2188613639C16438837 @default.
• W2188613639 hasConceptScore W2188613639C185592680 @default.
• W2188613639 hasConceptScore W2188613639C190283241 @default.
• W2188613639 hasConceptScore W2188613639C199835354 @default.
• W2188613639 hasConceptScore W2188613639C2778250585 @default.
• W2188613639 hasConceptScore W2188613639C2778437423 @default.
• W2188613639 hasConceptScore W2188613639C2781252693 @default.
• W2188613639 hasConceptScore W2188613639C29537977 @default.
• W2188613639 hasConceptScore W2188613639C50001416 @default.
• W2188613639 hasConceptScore W2188613639C502942594 @default.
• W2188613639 hasConceptScore W2188613639C55493867 @default.
• W2188613639 hasConceptScore W2188613639C62112901 @default.
• W2188613639 hasConceptScore W2188613639C86803240 @default.
• W2188613639 hasConceptScore W2188613639C9743823 @default.
• W2188613639 hasIssue "1" @default.
• W2188613639 hasLocation W21886136391 @default.
• W2188613639 hasOpenAccess W2188613639 @default.
• W2188613639 hasPrimaryLocation W21886136391 @default.
• W2188613639 hasRelatedWork W159837698 @default.
• W2188613639 hasRelatedWork W2005927939 @default.
• W2188613639 hasRelatedWork W2029535545 @default.
• W2188613639 hasRelatedWork W2132213196 @default.
• W2188613639 hasRelatedWork W2164695777 @default.
• W2188613639 hasRelatedWork W2188390423 @default.
• W2188613639 hasRelatedWork W2188613639 @default.
• W2188613639 hasRelatedWork W2322524550 @default.
• W2188613639 hasRelatedWork W2376313276 @default.
• W2188613639 hasRelatedWork W2527948228 @default.
• W2188613639 hasVolume "3" @default.
• W2188613639 isParatext "false" @default.

• next