FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2188630891> ?p ?o ?g. }

• W2188630891 abstract "Consumption of a naturally occurring polyphenol, in moderate amounts, has been suggested to be beneficial to health. The present study investigated the efficacy of red wine on prevention of carbon tetrachloride (CCl4) induced acute hepatic injury i n wistar rats. Hepatic damage due to CCl4 intoxication was assessed by employing biochemical parameters, markers of hepatic oxidative damage were measured in terms of ROS, MDA, GSH and enzyme antioxidants (CAT, SOD, GPx) levels. Immune parameters (IgG1, IgG2, CD4, CD8), cytokines (IL-6, IL-10) and gene expressions of COX-2 and CYP2E1 were carried out. In addition, CCl4-induced pathological changes in liver were evaluated by histopathological studies. Pre-treatment with red wine significantly prevented increase in ser um hepatic enzymatic activities, ROS, MDA levels as well as depletion of glutathione. Pre-treatment of red wine normalized the antioxidant enzyme activities in CCl4 intoxicated rats. Our data revealed that pre-treatment with red wine normalized the levels of interleukin 6 &10, IgG and CD4 cell count. Pre-treatment of red wine significantly prevented COX-2 inflammatory response and the up regulation of CYP2E1 expression as well. Histopathological findings also revealed the protective effect of red wine . Our findings provide evidence to demonstrate that red wine has a potent hepato-protective effect on CCl4-induced liver injury in rats thr ough its antioxidative, immuno- modulatory and anti-inflammatory activity." @default.
• W2188630891 created "2016-06-24" @default.
• W2188630891 creator A5010559338 @default.
• W2188630891 creator A5071504923 @default.
• W2188630891 creator A5083039810 @default.
• W2188630891 date "2011-01-01" @default.
• W2188630891 modified "2023-09-23" @default.
• W2188630891 title "Red wine ameliorates CCl4 - induced acute liver injury in rats" @default.
• W2188630891 cites W1962242957 @default.
• W2188630891 cites W1974795861 @default.
• W2188630891 cites W1981007299 @default.
• W2188630891 cites W1984454286 @default.
• W2188630891 cites W2008155315 @default.
• W2188630891 cites W2017778025 @default.
• W2188630891 cites W2018018767 @default.
• W2188630891 cites W2025842042 @default.
• W2188630891 cites W2030727522 @default.
• W2188630891 cites W2034898503 @default.
• W2188630891 cites W2043180366 @default.
• W2188630891 cites W2048587701 @default.
• W2188630891 cites W2049393985 @default.
• W2188630891 cites W206274772 @default.
• W2188630891 cites W2064462146 @default.
• W2188630891 cites W2071431076 @default.
• W2188630891 cites W2076753037 @default.
• W2188630891 cites W2077846279 @default.
• W2188630891 cites W2078166953 @default.
• W2188630891 cites W2081002898 @default.
• W2188630891 cites W2084494768 @default.
• W2188630891 cites W2086289116 @default.
• W2188630891 cites W2091754536 @default.
• W2188630891 cites W2093283937 @default.
• W2188630891 cites W2095802468 @default.
• W2188630891 cites W2111525805 @default.
• W2188630891 cites W2111781671 @default.
• W2188630891 cites W2116342732 @default.
• W2188630891 cites W2142374820 @default.
• W2188630891 cites W2143900711 @default.
• W2188630891 cites W2159374042 @default.
• W2188630891 cites W2410799507 @default.
• W2188630891 hasPublicationYear "2011" @default.
• W2188630891 type Work @default.
• W2188630891 sameAs 2188630891 @default.
• W2188630891 citedByCount "2" @default.
• W2188630891 countsByYear W21886308912015 @default.
• W2188630891 crossrefType "journal-article" @default.
• W2188630891 hasAuthorship W2188630891A5010559338 @default.
• W2188630891 hasAuthorship W2188630891A5071504923 @default.
• W2188630891 hasAuthorship W2188630891A5083039810 @default.
• W2188630891 hasConcept C102124568 @default.
• W2188630891 hasConcept C178790620 @default.
• W2188630891 hasConcept C181199279 @default.
• W2188630891 hasConcept C185592680 @default.
• W2188630891 hasConcept C203014093 @default.
• W2188630891 hasConcept C2776151105 @default.
• W2188630891 hasConcept C2776637226 @default.
• W2188630891 hasConcept C2777359374 @default.
• W2188630891 hasConcept C2778004101 @default.
• W2188630891 hasConcept C31903555 @default.
• W2188630891 hasConcept C538909803 @default.
• W2188630891 hasConcept C55493867 @default.
• W2188630891 hasConcept C55952523 @default.
• W2188630891 hasConcept C71924100 @default.
• W2188630891 hasConcept C98274493 @default.
• W2188630891 hasConceptScore W2188630891C102124568 @default.
• W2188630891 hasConceptScore W2188630891C178790620 @default.
• W2188630891 hasConceptScore W2188630891C181199279 @default.
• W2188630891 hasConceptScore W2188630891C185592680 @default.
• W2188630891 hasConceptScore W2188630891C203014093 @default.
• W2188630891 hasConceptScore W2188630891C2776151105 @default.
• W2188630891 hasConceptScore W2188630891C2776637226 @default.
• W2188630891 hasConceptScore W2188630891C2777359374 @default.
• W2188630891 hasConceptScore W2188630891C2778004101 @default.
• W2188630891 hasConceptScore W2188630891C31903555 @default.
• W2188630891 hasConceptScore W2188630891C538909803 @default.
• W2188630891 hasConceptScore W2188630891C55493867 @default.
• W2188630891 hasConceptScore W2188630891C55952523 @default.
• W2188630891 hasConceptScore W2188630891C71924100 @default.
• W2188630891 hasConceptScore W2188630891C98274493 @default.
• W2188630891 hasLocation W21886308911 @default.
• W2188630891 hasOpenAccess W2188630891 @default.
• W2188630891 hasPrimaryLocation W21886308911 @default.
• W2188630891 hasRelatedWork W1963685031 @default.
• W2188630891 hasRelatedWork W1973888968 @default.
• W2188630891 hasRelatedWork W2026101980 @default.
• W2188630891 hasRelatedWork W2060962359 @default.
• W2188630891 hasRelatedWork W2078406367 @default.
• W2188630891 hasRelatedWork W2082221599 @default.
• W2188630891 hasRelatedWork W2094864105 @default.
• W2188630891 hasRelatedWork W2326929665 @default.
• W2188630891 hasRelatedWork W2377544249 @default.
• W2188630891 hasRelatedWork W2475612859 @default.
• W2188630891 hasRelatedWork W2611028551 @default.
• W2188630891 hasRelatedWork W2767748577 @default.
• W2188630891 hasRelatedWork W2903236579 @default.
• W2188630891 hasRelatedWork W2911660744 @default.
• W2188630891 hasRelatedWork W2980707255 @default.
• W2188630891 hasRelatedWork W2996410192 @default.
• W2188630891 hasRelatedWork W3085318091 @default.
• W2188630891 hasRelatedWork W3137854132 @default.

• next