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- W2188631198 abstract "Candida species are the most important causes of fu ngal infections in humans. Vulvovaginal Candidiasis (VVC) covers 20-25 percent of Vulvovaginal forms of infec tions in women. Candida albicans is the cause of most cases of VVC infection. VVC, especially in the recurrent for m, is a physical-mental illness that causes a varie ty of stresses in patients. Due to side effects of antifungal drugs and increas ing drug resistance to these yeasts, researches to find an herbal medicine with fewer side effects and more ef ficiency should be continued. This study aimed to exactly identify C. albicans species isolated from VVC pati ents and evaluate its drug sensitivity to Z. multiflora extract. 23 yeasts were Isolated from RVVC patients: 53% C. albicans (15 cases), 35 % C. glabrata (8 cases), and 13 % C. krusei (3 cases). After identification of the yeasts by phenotypic and genotypic methods, cell suspensi on with 5◊10 4 cells of C. albicans was prepared. Drug sensitivit y test performed according to Microdilution NCCLS ( CLSI) M27A method in the microplates with various concentrat ions of Z. multiflora extract. The results showed that the minimum inhibitory concentration (MIC) of the used Z. multiflora extract, for 11, 3, and 1 C. albicans strains, is 8718.75, 17437.5, and 34875 µg/ml, respectively. Ou r data indicated that this isolated yeasts species from RVVC patients has shown the sensitivity to Z. multiflora extract. It is hoped in the near future that this herbal med icine be the alternative of chemicals drugs and be used to t reat RVVC patients." @default.
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- W2188631198 date "2012-01-01" @default.
- W2188631198 modified "2023-09-24" @default.
- W2188631198 title "Identification of Candida albicans isolated from Recurrent VulvovaginalCandidiasis (RVVC) patients by PCR-RFLP method and its drug sensitivityto Zataria multiflora extract" @default.
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