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- W2188635587 abstract "Summary The ethanol extract of Anacardium occidentale L. ( Anacardiaceae ), was evaluated for antiasthmatic activity by using various animal models. The in vitro animal models like isolated goat tracheal chain preparation and isolated guinea pig ileum preparation were used to study basic mechanism by which extract shows relaxant activity. The ethyl acetate soluble part of ethanol extract showed significant relaxant effects (p<0.01) compared to histamine in both Goat tracheal and Guinea pig ileum preparation. Hence ethanolic extract was used for further in vivo models instead of ethyl acetate soluble part. The in vivo models used were Haloperidol induced catalepsy and milk induced leukocytosis in mice. The ethanol extract showed maximum protection (p<0.01) against catalepsy at dose of 375 mg/kg p.o. body weight. Biochemical estimations in Milk induced total leukocytosis count showed maximum decrease in total leukocyte count at dose of 250 mg/kg p.o. body weight. The activity was found to be decreased as the dose was increased. The results of these studies inspire usefulness of Ethanol extract of Anacardium occidentale L. in antiasthmatic treatment." @default.
- W2188635587 created "2016-06-24" @default.
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- W2188635587 date "2011-01-01" @default.
- W2188635587 modified "2023-09-27" @default.
- W2188635587 title "EVALUATIOOF ATIASTHMATIC ACTIVITY OF AACARDIUM OCCIDETALE L. LEAVES" @default.
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