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- W2188642214 abstract "An alcoholic patient presented with profound hyponatremia (serum sodium concentration, 96 mEq/L) caused by the combined effects of a thiazide diuretic, serotonin reuptake inhibitor, beer potomania, and hypovolemia. A computed tomographic scan of the brain was indistinguishable from one obtained 3 weeks earlier when he was normonatremic. Concurrent administration of 3% saline solution and desmopressin controlled the rate of correction to an average of 6 mEq/L daily and resulted in full neurologic recovery without evidence of osmotic demyelination. This case illustrates the value of controlled correction of profound hyponatremia. Am J Kidney Dis 56:774-779. © 2010 by the National Kidney Foundation, Inc. INDEX WORDS: Hyponatremia; desmopressin; antidiuretic hormone; hypertonic saline. Note from Feature Editor Jeffrey A. Kraut, MD: This article is part of a series of invited case discussions highlighting either the diagnosis or treatment of acidbase and electrolyte disorders. Advisory Board member Horacio Adrogue, MD, served as the Consulting Editor for this case. The present case discussion is the second of 2 articles discussing hyponatremia. In this article, Drs Sterns, Hix, and Silver present their approach to the treatment of hyponatremia; in the first teaching case, Drs Berl and Rastegar describe a physiologic-based approach to its diagnosis and evaluation. 1" @default.
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- W2188642214 date "2010-01-01" @default.
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- W2188642214 title "ACID-BASE AND ELECTROLYTE TEACHING CASE Treating Profound Hyponatremia: A Strategy for Controlled Correction" @default.
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