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- W2188664294 abstract "An 83 year old female was presented to the operating room for laparoscopic transverse loop colostomy for Ogilvie’s syndrome. The laboratory work up was significant with magnesium level of 1.7 mg/dl. The patient received 100mg of lidocaine, 140mg of propofol and 40mg of rocuroniumduring intubation. Subsequently, patient had received clindamycin 600 mg and gentamicin 80 mg and 4 grams of magnesium by infusion over a period of 30 minutes. During surgery, the patient did not receive any additional dose of rocuronium. At the end of the procedure, which lasted about 3hours, peripheral nerve stimulation showed no twitches. Patient stayed intubated and transported to post anesthesia care unit. Serum level of magnesium was checked and it was 3.2 mg/dl. After an hour (total of 4hrs. from the time the patient received rocuronium), the patient had 4/4 twitches with negative fade and was extubated. It has been reported in articles that magnesium could cause potentiation of neuromuscular blockade effect of rocuronium ranging from 45 to 55 minutes. It is believed that this article could be the first published case report where supplemental magnesium given in the perioperative period, with concomitant use of amino glycoside antibiotics has led to prolongation of neuromuscular blockade for 4 hours." @default.
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- W2188664294 date "2014-01-01" @default.
- W2188664294 modified "2023-09-27" @default.
- W2188664294 title "Potentiation of Neuromuscular Blockade Effect of Rocuronium for 4 Hours Due to Perioperative Gentamicin, Clindamycin and Magnesium Sulfate" @default.
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