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- W2188664461 abstract "Fever of unknown origin (FUO) has multiple causes. Scrub typhus is less known cause of FUO in India. There was high mortality in undiagnosed cases of FUO which lead to the diagnosis of scrub typhus. Scrub typhus is a rickettsial infection which is caused by Orientia tsutsugamushi and transmitted by the bite of the chigger of a mite. Present study done to know the prevalence of scrub typhus as a causative factor in FUO cases by detection of IgM antibodies by ELISA and rapid test. This study was done over a period of six months in Narayana medical college and hospital. 223 serum samples of FUO cases were analysed for IgM antibodies to Orientia tsutsugamushi along with dengue, malaria, typhoid, tuberculosis and brucellosis. Scrub typhus IgM antibodies by ELISA were detected in 93 (41.7%) patients. Scrub typhus positivity was significantly higher among female in comparison to males. Maximum positivity of scrub typhus was found in females of 46-60 years age group. There was 98% correlation between ELISA and rapid method. The laboratory parameters were abnormal in most of the patients as evident by thrombocytopenia, deranged liver functions and renal functions. The present study emphasizes the importance of scrub typhus among cases of FUO especially after rainy season and during early cooler months. K e y w o r d s Fever of unknown origin, Orientia tsutsugamushi, Elisa-enzyme linked immune sorbent assay, Rapid test, Scrub typhus" @default.
- W2188664461 created "2016-06-24" @default.
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- W2188664461 date "2015-01-01" @default.
- W2188664461 modified "2023-09-26" @default.
- W2188664461 title "FUO Cases Showing Prevalence of Scrub Typhus: A Comparative Study by ELISA and Rapid Test in a Tertiary Care Hospital in Andhra Pradesh , India" @default.
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