Matches in SemOpenAlex for { <https://semopenalex.org/work/W2188683208> ?p ?o ?g. }
- W2188683208 abstract "The ultimate goal of nanomedicine is to perform nanorobotic therapeutic procedures on specified individual cells comprising the human body. This paper reports the first theoretical scaling analysis and mission design for a cell repair nanorobot. One conceptually simple form of basic cell repair is chromosome replacement therapy (CRT), in which the entire chromatin content of the nucleus in a living cell is extracted and promptly replaced with a new set of prefabricated chromosomes which have been artificially manufactured as defect-free copies of the originals. The chromallocyte is a hypothetical mobile cell-repair nanorobot capable of limited vascular surface travel into the capillary bed of the targeted tissue or organ, followed by extravasation, histonatation, cytopenetration, and complete chromatin replacement in the nucleus of one target cell, and ending with a return to the bloodstream and subsequent extraction of the device from the body, completing the CRT mission. A single lozenge-shaped 69 micron 3 chromallocyte measures" @default.
- W2188683208 created "2016-06-24" @default.
- W2188683208 creator A5073546765 @default.
- W2188683208 date "2007-01-01" @default.
- W2188683208 modified "2023-09-26" @default.
- W2188683208 title "The Ideal Gene Delivery Vector: Chromallocytes, Cell Repair Nanorobots for Chromosome Replacement Therapy" @default.
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