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• W2188745221 abstract "The inner bark of Guettarda speciosa Linn. is used traditional Indian medicine to treat epilepsy. In present study the effect of ethanolic (95%) extract of Guettarda speciosa (EEGS) on antioxidant enzymes in rat brain after induction of seizures by MES and PTZ were observed. In which Superoxide dismutase, glutathione peroxidase, glutathione reductase and catalase was significantly (P<0.01) decreased in rat brain due to seizure and it was significantly (P<0.01) restored by administration of ethanol extract of Guettarda speciosa treated rats. Similar dose dependent results were obtained in PTZ model also. Whereas EEGS significantly decreased lipid peroxidation in both models. The anticonvulsant activity of EEGS might be presents of antioxidant properties and it delays the generation of free radical in MES & PTZ induced epilepsy." @default.
• W2188745221 created "2016-06-24" @default.
• W2188745221 creator A5071084871 @default.
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• W2188745221 date "2010-01-01" @default.
• W2188745221 modified "2023-09-23" @default.
• W2188745221 title "Effect of Guettarda speciosa extracts on antioxidant enzymes levels in rat brain after induction of seizures by MES and PTZ" @default.
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